Matches in SemOpenAlex for { <https://semopenalex.org/work/W164951198> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W164951198 endingPage "8" @default.
- W164951198 startingPage "84" @default.
- W164951198 abstract "To review the reports of fatal adverse drug reactions (ADRs) submitted to the Ontario Medical Association Adverse Drug Reactions Monitoring Program between 1990 and 1994; to identify drugs associated with fatal outcomes; and to assess the causative role of the drug in these events and the completeness of the data in these reports.Drug(s) identified on each ADR report as being responsible for the reaction were considered. Agents were classified by the Anatomical Therapeutic and Chemical classification system. The causality of each ADR report was evaluated by using an algorithmic rating scale.From the Ontario Medical Association database, 97 cases of ADRs that resulted in death were reviewed. One hundred fourteen medications were implicated as suspect drugs in the 97 deaths. The most commonly implicated drug classes were musculoskeletal agents, blood and blood-forming organ agents, and nervous system agents. Patients over 65 years of age comprised 60% of this series. After independent assessment as to causality, 13% of the cases were rated as probable, 86% were rated as possible and 1% were rated as doubtful. Seventy per cent of reports did not include information regarding medical history. Forty-two per cent of cases failed to provide adequate information to evaluate the feasibility of the time to onset of the ADR. The use of concomitant drugs was not reported in 12% of cases.The drugs most frequently implicated in fatal ADRs were consistent with those reported in other studies. Algorithmic causality assessments were of limited value in these reports. The completeness of the reports and adequacy of the information were poor. The type of reporting forms and information provided were not homogenous. There is a need to improve quality of reporting and harmonize reporting forms between monitoring bodies. The feasibility of unique data collection forms and obligatory reporting for fatal ADRs should be considered." @default.
- W164951198 created "2016-06-24" @default.
- W164951198 creator A5008411415 @default.
- W164951198 creator A5012549313 @default.
- W164951198 creator A5018303592 @default.
- W164951198 creator A5045619651 @default.
- W164951198 creator A5064009813 @default.
- W164951198 date "2001-01-01" @default.
- W164951198 modified "2023-10-18" @default.
- W164951198 title "Reporting of fatal adverse drug reactions." @default.
- W164951198 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11493936" @default.
- W164951198 hasPublicationYear "2001" @default.
- W164951198 type Work @default.
- W164951198 sameAs 164951198 @default.
- W164951198 citedByCount "7" @default.
- W164951198 countsByYear W1649511982014 @default.
- W164951198 countsByYear W1649511982015 @default.
- W164951198 countsByYear W1649511982022 @default.
- W164951198 crossrefType "journal-article" @default.
- W164951198 hasAuthorship W164951198A5008411415 @default.
- W164951198 hasAuthorship W164951198A5012549313 @default.
- W164951198 hasAuthorship W164951198A5018303592 @default.
- W164951198 hasAuthorship W164951198A5045619651 @default.
- W164951198 hasAuthorship W164951198A5064009813 @default.
- W164951198 hasConcept C121332964 @default.
- W164951198 hasConcept C126322002 @default.
- W164951198 hasConcept C177713679 @default.
- W164951198 hasConcept C195910791 @default.
- W164951198 hasConcept C197934379 @default.
- W164951198 hasConcept C206179267 @default.
- W164951198 hasConcept C2779384505 @default.
- W164951198 hasConcept C2780035454 @default.
- W164951198 hasConcept C2780542314 @default.
- W164951198 hasConcept C2993432071 @default.
- W164951198 hasConcept C62520636 @default.
- W164951198 hasConcept C64357122 @default.
- W164951198 hasConcept C71924100 @default.
- W164951198 hasConcept C98274493 @default.
- W164951198 hasConceptScore W164951198C121332964 @default.
- W164951198 hasConceptScore W164951198C126322002 @default.
- W164951198 hasConceptScore W164951198C177713679 @default.
- W164951198 hasConceptScore W164951198C195910791 @default.
- W164951198 hasConceptScore W164951198C197934379 @default.
- W164951198 hasConceptScore W164951198C206179267 @default.
- W164951198 hasConceptScore W164951198C2779384505 @default.
- W164951198 hasConceptScore W164951198C2780035454 @default.
- W164951198 hasConceptScore W164951198C2780542314 @default.
- W164951198 hasConceptScore W164951198C2993432071 @default.
- W164951198 hasConceptScore W164951198C62520636 @default.
- W164951198 hasConceptScore W164951198C64357122 @default.
- W164951198 hasConceptScore W164951198C71924100 @default.
- W164951198 hasConceptScore W164951198C98274493 @default.
- W164951198 hasIssue "2" @default.
- W164951198 hasLocation W1649511981 @default.
- W164951198 hasOpenAccess W164951198 @default.
- W164951198 hasPrimaryLocation W1649511981 @default.
- W164951198 hasRelatedWork W1500197269 @default.
- W164951198 hasRelatedWork W164951198 @default.
- W164951198 hasRelatedWork W2289010737 @default.
- W164951198 hasRelatedWork W2365235602 @default.
- W164951198 hasRelatedWork W2376067684 @default.
- W164951198 hasRelatedWork W2390458765 @default.
- W164951198 hasRelatedWork W2426351828 @default.
- W164951198 hasRelatedWork W56637561 @default.
- W164951198 hasRelatedWork W65191208 @default.
- W164951198 hasRelatedWork W99446073 @default.
- W164951198 hasVolume "8" @default.
- W164951198 isParatext "false" @default.
- W164951198 isRetracted "false" @default.
- W164951198 magId "164951198" @default.
- W164951198 workType "article" @default.