Matches in SemOpenAlex for { <https://semopenalex.org/work/W1649565553> ?p ?o ?g. }
- W1649565553 endingPage "3796" @default.
- W1649565553 startingPage "3790" @default.
- W1649565553 abstract "Reconstitution of lethally irradiated mice with a mixture of mouse and rat bone marrow cells (mouse + rat-->mouse) results in mixed xenogeneic chimerism and donor-specific tolerance. The current study demonstrates that mouse and rat T lymphocytes that have developed in xenogeneic chimeras are restricted to Ag presentation by mouse, but not rat, APC. Restriction to host Ags results in functional immunocompetence with generation of antiviral cytotoxic activity in vivo, within and across species barriers. These data demonstrate for the first time that the host thymus is sufficient to support development and positive selection of functional cross-species T lymphocytes. The superior immunocompetence, as compared with fully xenogeneic (rat-->mouse) chimeras, may prove to be of significant benefit in the clinical application of xenotransplantation to solid organ transplantation and immune reconstitution for AIDS." @default.
- W1649565553 created "2016-06-24" @default.
- W1649565553 creator A5000231201 @default.
- W1649565553 creator A5025653427 @default.
- W1649565553 creator A5027160232 @default.
- W1649565553 creator A5034925727 @default.
- W1649565553 creator A5053051899 @default.
- W1649565553 creator A5060383525 @default.
- W1649565553 creator A5074692390 @default.
- W1649565553 date "1998-04-15" @default.
- W1649565553 modified "2023-09-26" @default.
- W1649565553 title "Antiviral Cytotoxic Activity Across a Species Barrier in Mixed Xenogeneic Chimeras: Functional Restriction to Host MHC" @default.
- W1649565553 cites W1510276262 @default.
- W1649565553 cites W1523014057 @default.
- W1649565553 cites W1596267923 @default.
- W1649565553 cites W1597898543 @default.
- W1649565553 cites W1599176230 @default.
- W1649565553 cites W1967179992 @default.
- W1649565553 cites W1981638493 @default.
- W1649565553 cites W1984868405 @default.
- W1649565553 cites W1988009046 @default.
- W1649565553 cites W1994425461 @default.
- W1649565553 cites W2000696784 @default.
- W1649565553 cites W2005096752 @default.
- W1649565553 cites W2006519814 @default.
- W1649565553 cites W2020280306 @default.
- W1649565553 cites W2023053069 @default.
- W1649565553 cites W2024604633 @default.
- W1649565553 cites W2027119403 @default.
- W1649565553 cites W2048863509 @default.
- W1649565553 cites W2060767664 @default.
- W1649565553 cites W2062830954 @default.
- W1649565553 cites W2064835686 @default.
- W1649565553 cites W2072622418 @default.
- W1649565553 cites W2080909530 @default.
- W1649565553 cites W2085915950 @default.
- W1649565553 cites W2085979433 @default.
- W1649565553 cites W2103320120 @default.
- W1649565553 cites W2110272001 @default.
- W1649565553 cites W2120370266 @default.
- W1649565553 cites W2121285814 @default.
- W1649565553 cites W2123355963 @default.
- W1649565553 cites W2124120453 @default.
- W1649565553 cites W2148596010 @default.
- W1649565553 cites W2151470104 @default.
- W1649565553 cites W2160987601 @default.
- W1649565553 cites W2530023051 @default.
- W1649565553 cites W4233740873 @default.
- W1649565553 cites W4234684352 @default.
- W1649565553 cites W4238880890 @default.
- W1649565553 doi "https://doi.org/10.4049/jimmunol.160.8.3790" @default.
- W1649565553 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9558082" @default.
- W1649565553 hasPublicationYear "1998" @default.
- W1649565553 type Work @default.
- W1649565553 sameAs 1649565553 @default.
- W1649565553 citedByCount "14" @default.
- W1649565553 countsByYear W16495655532012 @default.
- W1649565553 countsByYear W16495655532014 @default.
- W1649565553 crossrefType "journal-article" @default.
- W1649565553 hasAuthorship W1649565553A5000231201 @default.
- W1649565553 hasAuthorship W1649565553A5025653427 @default.
- W1649565553 hasAuthorship W1649565553A5027160232 @default.
- W1649565553 hasAuthorship W1649565553A5034925727 @default.
- W1649565553 hasAuthorship W1649565553A5053051899 @default.
- W1649565553 hasAuthorship W1649565553A5060383525 @default.
- W1649565553 hasAuthorship W1649565553A5074692390 @default.
- W1649565553 hasBestOaLocation W16495655531 @default.
- W1649565553 hasConcept C141071460 @default.
- W1649565553 hasConcept C154317977 @default.
- W1649565553 hasConcept C159047783 @default.
- W1649565553 hasConcept C202751555 @default.
- W1649565553 hasConcept C203014093 @default.
- W1649565553 hasConcept C207936829 @default.
- W1649565553 hasConcept C2777422395 @default.
- W1649565553 hasConcept C2778442404 @default.
- W1649565553 hasConcept C2911091166 @default.
- W1649565553 hasConcept C54355233 @default.
- W1649565553 hasConcept C71924100 @default.
- W1649565553 hasConcept C86803240 @default.
- W1649565553 hasConcept C8891405 @default.
- W1649565553 hasConcept C95444343 @default.
- W1649565553 hasConceptScore W1649565553C141071460 @default.
- W1649565553 hasConceptScore W1649565553C154317977 @default.
- W1649565553 hasConceptScore W1649565553C159047783 @default.
- W1649565553 hasConceptScore W1649565553C202751555 @default.
- W1649565553 hasConceptScore W1649565553C203014093 @default.
- W1649565553 hasConceptScore W1649565553C207936829 @default.
- W1649565553 hasConceptScore W1649565553C2777422395 @default.
- W1649565553 hasConceptScore W1649565553C2778442404 @default.
- W1649565553 hasConceptScore W1649565553C2911091166 @default.
- W1649565553 hasConceptScore W1649565553C54355233 @default.
- W1649565553 hasConceptScore W1649565553C71924100 @default.
- W1649565553 hasConceptScore W1649565553C86803240 @default.
- W1649565553 hasConceptScore W1649565553C8891405 @default.
- W1649565553 hasConceptScore W1649565553C95444343 @default.
- W1649565553 hasIssue "8" @default.
- W1649565553 hasLocation W16495655531 @default.
- W1649565553 hasLocation W16495655532 @default.