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• W165087685 abstract "Variation in human behavior may be caused by differences in genotype and by non-genetic differences (“environment”) between individuals. The relative contributions of genotype (G) and environment (E) to phenotypic variation can be assessed with the classical twin design. We illustrate this approach with longitudinal data collected in 5 and 2-year-old Dutch twins. At age 5 data on cognitive abilities as assessed with a standard intelligence test (IQ), working memory, selective and sustained attention, and attention problems were collected in 237 twin pairs. Seven years later, 72 twin pairs participated again when they were 2 years old and underwent a similar protocol. Results showed that variation in all phenotypes was influenced by genetic factors. For IQ the heritability estimates increased from 30% at age 5, to 80% at age 2. For executive functioning performance genetic factors accounted for around 50% of the variance at both ages. Attention problems showed high heritabilities (above 60%) at both ages, for maternal and teacher ratings. Longitudinal analyses revealed that executive functioning during childhood was weakly correlated with IQ scores at age 2. Attention problems during childhood, as rated by the mother and the teacher were stronger predictors (r = -0.28 and -0.36, respectively). This association could be attributed to a partly overlapping set of genes influencing attention problems at age 5 and IQ at age 2. IQ performance at age 5 was the best predictor of IQ at age 2. IQ at both ages was influenced by the same genes, whose influence was amplified during development." @default.
• W165087685 created "2016-06-24" @default.
• W165087685 creator A5014833007 @default.
• W165087685 date "2007-01-01" @default.
• W165087685 modified "2023-09-26" @default.
• W165087685 title "Genetics of attention and executive functioning" @default.
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