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• W1652800543 abstract "Tuberculosis is a disease of humans and animals that is caused by the Mycobacterium tuberculosis complex (MTC). Tuberculosis is typically spread through the airborne route via droplet nuclei that are inhaled into the lungs. The majority of exposed hosts do not become infected, and the majority of infected hosts do not progress to clinically evident tuberculosis disease. However, when active tuberculosis disease does occur, it results in severe illness that is often highly contagious, commonly results in permanent damage to the lungs and other tissues, and frequently is eventually fatal without appropriate treatment. Although intraspecies (i.e., human-to-human and animal-to-animal) transmission is most common in tuberculosis epidemiology, interspecies (e.g., animal-to-human or human-to-animal) transmission is an important source of tuberculosis infections, particularly in developing areas of the world without fully developed bovine tuberculosis eradication programs and widespread pasteurization of milk. Zoonotic tuberculosis caused by Mycobacterium bovis is more common than zoonotic tuberculosis caused by other species of MTC, and tuberculosis disease caused by M. bovis infections often involve the alimentary tract, reflecting the role of ingestion in the transmission of M. bovis. Although rare, M. tuberculosis does play a role in transmission of tuberculosis to humans from animals such as nonhuman primates and elephants. As M. tuberculosis is host adapted to humans, infections with this MTC species in animals are generally considered to be the result of transmission from humans to animals. Prevention and control of both intraspecies and zoonotic transmission of MTC is important to eventually eliminating tuberculosis in human and domestic animal populations." @default.
• W1652800543 created "2016-06-24" @default.
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• W1652800543 date "2014-02-14" @default.
• W1652800543 modified "2023-09-28" @default.
• W1652800543 title "Public health significance of zoonotic tuberculosis caused by the <i>Mycobacterium tuberculosis</i> complex" @default.
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• W1652800543 doi "https://doi.org/10.1002/9781118474310.ch3" @default.
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