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- W1653877244 abstract "The human serum albumin microsphere (HSA microsphere) is biodegradable and biocompatible, the SPECT/CT imaging and biodistribution of 188Re-HSA microspheres using new radio labeling process were investigated in a GP7TB hepatoma rat model. The labeling efficiency of the 188Re-HSA microspheres using new radio labeling process was about 97%. The levels of radioactivity within the liver peaked at 1 h (68.325777±1.896218 %ID/organ) and then declined slowly. With image analysis, the highest uptake in liver was 69.9±3.8 %ID/organ and 59.7±5.7 %ID/organ at 48 and 72 h after administration of 188Re-HSA microspheres via TACE. The liver uptake of 188Re-HSA microspheres was steadily maintained that to increase the radioactivity to directly give damage to tumor cells. These results showed potential benefit and advantage of 188Re-HSA microspheres via liver transarterial chemoembolization (TACE) for treatment of Hepatocellular carcinoma." @default.
- W1653877244 created "2016-06-24" @default.
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- W1653877244 date "2015-09-01" @default.
- W1653877244 modified "2023-09-22" @default.
- W1653877244 title "NanoSPECT/CT imaging and biodistribution of <sup>188</sup>Re-HSA microspheres using new radio labeling process in a GP7TB hepatoma rats model (Imaging and Biodistribution of <sup>188</sup>Re-HSA microspheres)" @default.
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- W1653877244 doi "https://doi.org/10.1109/ist.2015.7294528" @default.
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