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- W165394443 abstract "This chapter discusses the relation between steroid hormones and breast cancer. It has been recognized for many years that, at least in their initial stages, some human tumors that arise from hormone-sensitive tissues retain some of the original characteristics of the cells from which they were derived. The better differentiated a tumor is and the more hormone-sensitive the original parent tissue is, the more likely a favorable response to hormone therapy is. Endocrine treatment is most effective in patients having slow-growing tumors. The whole question of the interaction of hormone-sensitive tumors with the endocrine status of the host is a fascinating one that remains to be resolved. Clinical experience has shown that tumors may respond either to oestrogen or to androgen therapy, depending on the tumor–host relationship of a particular patient. Although steroid therapy is well established in clinical practice, the fundamental mechanism by which these hormones exert their effect is still not completely understood." @default.
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- W165394443 date "1974-01-01" @default.
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- W165394443 title "Steroid Hormones and Breast Cancer" @default.
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- W165394443 doi "https://doi.org/10.1016/b978-0-12-037504-2.50009-2" @default.
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