Matches in SemOpenAlex for { <https://semopenalex.org/work/W165452616> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W165452616 abstract "Lysophosphatidylcholine: lysophosphatidylcholine acyltransferase is an enzyme that catalyses two reactions: hydrolysis of lysophosphatidylcholine and transacylation between two molecules of lysophosphatidylcholine to give disaturated phosphatidylcholine. Following the kinetic model previously proposed for this enzyme [Martín, Pérez-Gil, Acebal & Arche (1990) Biochem. J. 266, 47-53], the values of essential pK values in free enzyme and substrate-enzyme complexes have now been determined. The chemical mechanism of catalysis was dependent on the deprotonation of a histidine residue with pK about 5.7. This result was supported by the perturbation of pK values by addition of organic solvent. Very high and exothermic enthalpy of ionization was measured, indicating that a conformational re-arrangement in the enzyme accompanies the ionization of the essential histidine residue. These results, as well as the results from previous studies, enabled the proposal of a chemical mechanism for the enzymic reactions catalysed by lysophosphatidylcholine: lysophosphatidylcholine acyltransferase from rabbit lung." @default.
- W165452616 created "2016-06-24" @default.
- W165452616 creator A5046250168 @default.
- W165452616 creator A5047407771 @default.
- W165452616 creator A5053988731 @default.
- W165452616 creator A5086428854 @default.
- W165452616 date "1990-09-15" @default.
- W165452616 modified "2023-10-02" @default.
- W165452616 title "Chemical mechanism of lysophosphatidylcholine: lysophosphatidylcholine acyltransferase from rabbit lung. pH-dependence of kinetic parameters" @default.
- W165452616 cites W111960104 @default.
- W165452616 cites W1248348299 @default.
- W165452616 cites W1526775414 @default.
- W165452616 cites W1904681278 @default.
- W165452616 cites W1935994455 @default.
- W165452616 cites W1988071116 @default.
- W165452616 cites W2006105337 @default.
- W165452616 cites W2008706866 @default.
- W165452616 cites W2028893813 @default.
- W165452616 cites W2046163248 @default.
- W165452616 cites W2066839442 @default.
- W165452616 cites W2078502816 @default.
- W165452616 cites W2079195833 @default.
- W165452616 cites W2080355135 @default.
- W165452616 cites W2084514212 @default.
- W165452616 cites W2086925743 @default.
- W165452616 cites W2087186724 @default.
- W165452616 cites W2090318245 @default.
- W165452616 cites W2200991233 @default.
- W165452616 cites W2229689108 @default.
- W165452616 cites W2403297264 @default.
- W165452616 cites W2407718618 @default.
- W165452616 cites W2470324186 @default.
- W165452616 doi "https://doi.org/10.1042/bj2700761" @default.
- W165452616 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1131797" @default.
- W165452616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2241908" @default.
- W165452616 hasPublicationYear "1990" @default.
- W165452616 type Work @default.
- W165452616 sameAs 165452616 @default.
- W165452616 citedByCount "4" @default.
- W165452616 crossrefType "journal-article" @default.
- W165452616 hasAuthorship W165452616A5046250168 @default.
- W165452616 hasAuthorship W165452616A5047407771 @default.
- W165452616 hasAuthorship W165452616A5053988731 @default.
- W165452616 hasAuthorship W165452616A5086428854 @default.
- W165452616 hasBestOaLocation W1654526162 @default.
- W165452616 hasConcept C118629725 @default.
- W165452616 hasConcept C145148216 @default.
- W165452616 hasConcept C178790620 @default.
- W165452616 hasConcept C181199279 @default.
- W165452616 hasConcept C185592680 @default.
- W165452616 hasConcept C2776330855 @default.
- W165452616 hasConcept C2778460671 @default.
- W165452616 hasConcept C2778596009 @default.
- W165452616 hasConcept C2778918659 @default.
- W165452616 hasConcept C41183919 @default.
- W165452616 hasConcept C41625074 @default.
- W165452616 hasConcept C55493867 @default.
- W165452616 hasConcept C71240020 @default.
- W165452616 hasConceptScore W165452616C118629725 @default.
- W165452616 hasConceptScore W165452616C145148216 @default.
- W165452616 hasConceptScore W165452616C178790620 @default.
- W165452616 hasConceptScore W165452616C181199279 @default.
- W165452616 hasConceptScore W165452616C185592680 @default.
- W165452616 hasConceptScore W165452616C2776330855 @default.
- W165452616 hasConceptScore W165452616C2778460671 @default.
- W165452616 hasConceptScore W165452616C2778596009 @default.
- W165452616 hasConceptScore W165452616C2778918659 @default.
- W165452616 hasConceptScore W165452616C41183919 @default.
- W165452616 hasConceptScore W165452616C41625074 @default.
- W165452616 hasConceptScore W165452616C55493867 @default.
- W165452616 hasConceptScore W165452616C71240020 @default.
- W165452616 hasLocation W1654526161 @default.
- W165452616 hasLocation W1654526162 @default.
- W165452616 hasLocation W1654526163 @default.
- W165452616 hasLocation W1654526164 @default.
- W165452616 hasOpenAccess W165452616 @default.
- W165452616 hasPrimaryLocation W1654526161 @default.
- W165452616 hasRelatedWork W1519820833 @default.
- W165452616 hasRelatedWork W1619794196 @default.
- W165452616 hasRelatedWork W1644435435 @default.
- W165452616 hasRelatedWork W1968338734 @default.
- W165452616 hasRelatedWork W2015369153 @default.
- W165452616 hasRelatedWork W2091815043 @default.
- W165452616 hasRelatedWork W2139062079 @default.
- W165452616 hasRelatedWork W2290318361 @default.
- W165452616 hasRelatedWork W2437348584 @default.
- W165452616 hasRelatedWork W2591622783 @default.
- W165452616 isParatext "false" @default.
- W165452616 isRetracted "false" @default.
- W165452616 magId "165452616" @default.
- W165452616 workType "article" @default.