Matches in SemOpenAlex for { <https://semopenalex.org/work/W165514063> ?p ?o ?g. }
- W165514063 endingPage "4613" @default.
- W165514063 startingPage "4603" @default.
- W165514063 abstract "Research Article1 December 1993free access Chromatin transitions during activation and repression of galactose-regulated genes in yeast. G. Cavalli G. Cavalli Institut für Zellbiologie, ETH-Hönggerberg, Zürich, Switzerland. Search for more papers by this author F. Thoma F. Thoma Institut für Zellbiologie, ETH-Hönggerberg, Zürich, Switzerland. Search for more papers by this author G. Cavalli G. Cavalli Institut für Zellbiologie, ETH-Hönggerberg, Zürich, Switzerland. Search for more papers by this author F. Thoma F. Thoma Institut für Zellbiologie, ETH-Hönggerberg, Zürich, Switzerland. Search for more papers by this author Author Information G. Cavalli1 and F. Thoma1 1Institut für Zellbiologie, ETH-Hönggerberg, Zürich, Switzerland. The EMBO Journal (1993)12:4603-4613https://doi.org/10.1002/j.1460-2075.1993.tb06149.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info To study the fate of nucleosomes during transcription, a yeast gene ‘GAL-URARIB’ was constructed which is tightly regulated by the GAL1 promoter and shows in its inactive state a series of positioned nucleosomes that are sensitive for monitoring structural changes by micrococcal nuclease. Upon transcriptional activation, nucleosome positions were lost, but a residual nucleosomal repeat with an altered repeat length and no changes in psoralen accessibility measured by a band shift assay indicated that nucleosomes were present but rearranged on the transcribed gene. When chromatin was prepared 10 or 50 min after glucose repression, nucleosomes were repositioned in a large fraction of the population by a rapid process which most likely did not depend on histone synthesis or DNA replication. However, complete regeneration of the inactive structure and repeat length was observed after one cell generation (2.5 h) suggesting that in this step some missing histones were replaced. The results are consistent with a local dissociation of nucleosomes at the site of the polymerase followed by a rapid reassembly into nucleosomes behind it. The data are further supported by analysis of the chromosomal GAL1, GAL7 and GAL10 genes. Previous ArticleNext Article Volume 12Issue 121 December 1993In this issue RelatedDetailsLoading ..." @default.
- W165514063 created "2016-06-24" @default.
- W165514063 creator A5082592224 @default.
- W165514063 creator A5087766645 @default.
- W165514063 date "1993-12-01" @default.
- W165514063 modified "2023-09-29" @default.
- W165514063 title "Chromatin transitions during activation and repression of galactose-regulated genes in yeast." @default.
- W165514063 cites W1482823664 @default.
- W165514063 cites W1502128823 @default.
- W165514063 cites W1515229511 @default.
- W165514063 cites W1554360427 @default.
- W165514063 cites W1560540551 @default.
- W165514063 cites W1567029125 @default.
- W165514063 cites W160239957 @default.
- W165514063 cites W1767747534 @default.
- W165514063 cites W1817418355 @default.
- W165514063 cites W1855382658 @default.
- W165514063 cites W1952811255 @default.
- W165514063 cites W1964704331 @default.
- W165514063 cites W1964876650 @default.
- W165514063 cites W1965501031 @default.
- W165514063 cites W1966046539 @default.
- W165514063 cites W1966074474 @default.
- W165514063 cites W1970981824 @default.
- W165514063 cites W1973782344 @default.
- W165514063 cites W1984221059 @default.
- W165514063 cites W1985195944 @default.
- W165514063 cites W2008143037 @default.
- W165514063 cites W2008656832 @default.
- W165514063 cites W2013083223 @default.
- W165514063 cites W2014841064 @default.
- W165514063 cites W2016556312 @default.
- W165514063 cites W2017871787 @default.
- W165514063 cites W2020805433 @default.
- W165514063 cites W2023928518 @default.
- W165514063 cites W2026030777 @default.
- W165514063 cites W2026782063 @default.
- W165514063 cites W2027045042 @default.
- W165514063 cites W2027067909 @default.
- W165514063 cites W2027854680 @default.
- W165514063 cites W2029557602 @default.
- W165514063 cites W2032536951 @default.
- W165514063 cites W2034678820 @default.
- W165514063 cites W2035276244 @default.
- W165514063 cites W2036339125 @default.
- W165514063 cites W2045251366 @default.
- W165514063 cites W2047049388 @default.
- W165514063 cites W2050577419 @default.
- W165514063 cites W2060357264 @default.
- W165514063 cites W2060827555 @default.
- W165514063 cites W2064262495 @default.
- W165514063 cites W2066997247 @default.
- W165514063 cites W2067906688 @default.
- W165514063 cites W2070219093 @default.
- W165514063 cites W2071166961 @default.
- W165514063 cites W2073446257 @default.
- W165514063 cites W2102131815 @default.
- W165514063 cites W2105487716 @default.
- W165514063 cites W2129872577 @default.
- W165514063 cites W2133306685 @default.
- W165514063 cites W2134485635 @default.
- W165514063 cites W2183113301 @default.
- W165514063 cites W4211121711 @default.
- W165514063 cites W55548661 @default.
- W165514063 cites W981450589 @default.
- W165514063 doi "https://doi.org/10.1002/j.1460-2075.1993.tb06149.x" @default.
- W165514063 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/413896" @default.
- W165514063 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8223470" @default.
- W165514063 hasPublicationYear "1993" @default.
- W165514063 type Work @default.
- W165514063 sameAs 165514063 @default.
- W165514063 citedByCount "106" @default.
- W165514063 countsByYear W1655140632012 @default.
- W165514063 countsByYear W1655140632013 @default.
- W165514063 countsByYear W1655140632016 @default.
- W165514063 countsByYear W1655140632017 @default.
- W165514063 countsByYear W1655140632022 @default.
- W165514063 crossrefType "journal-article" @default.
- W165514063 hasAuthorship W165514063A5082592224 @default.
- W165514063 hasAuthorship W165514063A5087766645 @default.
- W165514063 hasBestOaLocation W1655140632 @default.
- W165514063 hasConcept C104317684 @default.
- W165514063 hasConcept C139024627 @default.
- W165514063 hasConcept C150194340 @default.
- W165514063 hasConcept C153911025 @default.
- W165514063 hasConcept C186310378 @default.
- W165514063 hasConcept C54355233 @default.
- W165514063 hasConcept C83640560 @default.
- W165514063 hasConcept C84772758 @default.
- W165514063 hasConcept C86803240 @default.
- W165514063 hasConceptScore W165514063C104317684 @default.
- W165514063 hasConceptScore W165514063C139024627 @default.
- W165514063 hasConceptScore W165514063C150194340 @default.
- W165514063 hasConceptScore W165514063C153911025 @default.
- W165514063 hasConceptScore W165514063C186310378 @default.
- W165514063 hasConceptScore W165514063C54355233 @default.
- W165514063 hasConceptScore W165514063C83640560 @default.
- W165514063 hasConceptScore W165514063C84772758 @default.