Matches in SemOpenAlex for { <https://semopenalex.org/work/W1656151818> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W1656151818 endingPage "2713" @default.
- W1656151818 startingPage "2708" @default.
- W1656151818 abstract "L-A is a 4.6-kilobase double-stranded RNA virus of Saccharomyces cerevisiae. The in vitro L-A replication reaction ((-)-strand synthesis) requires an internal site 400 bases from the 3' end in addition to the 3'-terminal 30 nucleotides of the L-A (+)-single-stranded RNA. Elimination of the internal site reduces the template activity 5-10-fold. Here we investigate how the internal site can stimulate the replication reaction which starts at the 3' end of the template. When these two sites are split into two distinct RNA molecules, the internal site can no longer stimulate replication (no trans-activation). However, establishment of an intermolecular hydrogen bonding between these RNAs restored the replication-enhancing activity of the internal site. This result is consistent with a model wherein L-A's RNA polymerase interacts first with the internal site and then with the 3' end site by either looping or by a local dissociation-reassociation mechanism. These results, however, clearly eliminate anchored tracking and sliding models which require continuity of the RNA molecule between these two cis sites." @default.
- W1656151818 created "2016-06-24" @default.
- W1656151818 creator A5051003882 @default.
- W1656151818 creator A5068072238 @default.
- W1656151818 date "1992-02-01" @default.
- W1656151818 modified "2023-09-30" @default.
- W1656151818 title "Interaction of two cis sites with the RNA replicase of the yeast L-A virus." @default.
- W1656151818 cites W1486587808 @default.
- W1656151818 cites W1500813242 @default.
- W1656151818 cites W1550334320 @default.
- W1656151818 cites W1573218071 @default.
- W1656151818 cites W1607317971 @default.
- W1656151818 cites W1966443347 @default.
- W1656151818 cites W1967737680 @default.
- W1656151818 cites W1980336356 @default.
- W1656151818 cites W1984529047 @default.
- W1656151818 cites W2014035813 @default.
- W1656151818 cites W2016331651 @default.
- W1656151818 cites W2024093259 @default.
- W1656151818 cites W2025896371 @default.
- W1656151818 cites W2033777731 @default.
- W1656151818 cites W2036280947 @default.
- W1656151818 cites W2036931150 @default.
- W1656151818 cites W2040843640 @default.
- W1656151818 cites W2044318526 @default.
- W1656151818 cites W2048668097 @default.
- W1656151818 cites W2052455407 @default.
- W1656151818 cites W2056463259 @default.
- W1656151818 cites W2072973625 @default.
- W1656151818 cites W2083155778 @default.
- W1656151818 cites W2346337789 @default.
- W1656151818 cites W258711819 @default.
- W1656151818 doi "https://doi.org/10.1016/s0021-9258(18)45937-6" @default.
- W1656151818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1733966" @default.
- W1656151818 hasPublicationYear "1992" @default.
- W1656151818 type Work @default.
- W1656151818 sameAs 1656151818 @default.
- W1656151818 citedByCount "30" @default.
- W1656151818 countsByYear W16561518182012 @default.
- W1656151818 countsByYear W16561518182013 @default.
- W1656151818 countsByYear W16561518182018 @default.
- W1656151818 crossrefType "journal-article" @default.
- W1656151818 hasAuthorship W1656151818A5051003882 @default.
- W1656151818 hasAuthorship W1656151818A5068072238 @default.
- W1656151818 hasBestOaLocation W16561518181 @default.
- W1656151818 hasConcept C104317684 @default.
- W1656151818 hasConcept C159047783 @default.
- W1656151818 hasConcept C2779222958 @default.
- W1656151818 hasConcept C41258723 @default.
- W1656151818 hasConcept C54355233 @default.
- W1656151818 hasConcept C67705224 @default.
- W1656151818 hasConcept C86803240 @default.
- W1656151818 hasConceptScore W1656151818C104317684 @default.
- W1656151818 hasConceptScore W1656151818C159047783 @default.
- W1656151818 hasConceptScore W1656151818C2779222958 @default.
- W1656151818 hasConceptScore W1656151818C41258723 @default.
- W1656151818 hasConceptScore W1656151818C54355233 @default.
- W1656151818 hasConceptScore W1656151818C67705224 @default.
- W1656151818 hasConceptScore W1656151818C86803240 @default.
- W1656151818 hasIssue "4" @default.
- W1656151818 hasLocation W16561518181 @default.
- W1656151818 hasOpenAccess W1656151818 @default.
- W1656151818 hasPrimaryLocation W16561518181 @default.
- W1656151818 hasRelatedWork W1920751942 @default.
- W1656151818 hasRelatedWork W1991523530 @default.
- W1656151818 hasRelatedWork W2002128513 @default.
- W1656151818 hasRelatedWork W2020824267 @default.
- W1656151818 hasRelatedWork W2031436818 @default.
- W1656151818 hasRelatedWork W2057739827 @default.
- W1656151818 hasRelatedWork W2075354549 @default.
- W1656151818 hasRelatedWork W2123268304 @default.
- W1656151818 hasRelatedWork W2917539084 @default.
- W1656151818 hasRelatedWork W2092874662 @default.
- W1656151818 hasVolume "267" @default.
- W1656151818 isParatext "false" @default.
- W1656151818 isRetracted "false" @default.
- W1656151818 magId "1656151818" @default.
- W1656151818 workType "article" @default.