FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1657151749> ?p ?o ?g. }

• W1657151749 endingPage "1913" @default.
• W1657151749 startingPage "1906" @default.
• W1657151749 abstract "We aimed to evaluate all-cause mortality of middle-aged and elderly subjects diagnosed with dementia and treated with psychotropic drugs as compared with controls subjects. Using data from the Danish National Patient Registry, n=26,821 adults with a diagnosis of dementia were included. They were compared with 44,286 control subjects with a minimum follow-up of four years and matched on age, gender, marital status, and community location. Information about psychotropic medication use (benzodiazepines, antidepressants, antipsychotics) was obtained from the Danish Medicinal Product Statistics. All-cause mortality was higher in patients with dementia as compared to control subjects. Mortality hazard ratios were increased for subjects prescribed serotonergic antidepressant drugs (respectively, HR=1.355 (SD=0.023), P=0.001 in patients; HR=1.808 (0.033), P<0.001 in controls), tricyclic antidepressants (HR=1.004 (0.046), P=0.925; HR=1.406 (0.061), P<0.001), benzodiazepines (HR=1.131 (0.039), P=0.060); HR=1.362 (0.028), P<0.001), benzodiazepine-like drugs (HR=1.108 (0.031), P=0.078; HR=1.564 (0.037, P<0.001), first-generation antipsychotics (HR=1.183 (0.074), P=0.022; HR=2.026 (0.114), P<0.001), and second-generation antipsychotics (HR=1.380 (0.042), P<0.001; HR=1.785 (0.088), P<0.001), as compared with no drug use. Interaction analysis suggested statistically significantly higher mortality hazard ratios for most classes of psychotropic drugs in controls than in dementia patients. We found that use of psychotropic drugs is associated with increased all-cause mortality in both patients with dementia and control subjects. Thus, the frequently reported increased mortality with antipsychotic drugs in dementia is not restricted to subjects with impaired cognition and is not restricted to only one class of psychotropic drugs." @default.
• W1657151749 created "2016-06-24" @default.
• W1657151749 creator A5035038268 @default.
• W1657151749 creator A5043345480 @default.
• W1657151749 creator A5049561335 @default.
• W1657151749 creator A5087489056 @default.
• W1657151749 date "2015-11-01" @default.
• W1657151749 modified "2023-09-24" @default.
• W1657151749 title "Increased all-cause mortality with use of psychotropic medication in dementia patients and controls: A population-based register study" @default.
• W1657151749 cites W1498297631 @default.
• W1657151749 cites W1513548425 @default.
• W1657151749 cites W1583101023 @default.
• W1657151749 cites W1607578860 @default.
• W1657151749 cites W1776850319 @default.
• W1657151749 cites W1964898519 @default.
• W1657151749 cites W1970853121 @default.
• W1657151749 cites W1972700158 @default.
• W1657151749 cites W1983162522 @default.
• W1657151749 cites W1988834862 @default.
• W1657151749 cites W2000445173 @default.
• W1657151749 cites W2003958103 @default.
• W1657151749 cites W2013946630 @default.
• W1657151749 cites W2025196207 @default.
• W1657151749 cites W2044429484 @default.
• W1657151749 cites W2046877484 @default.
• W1657151749 cites W2053088224 @default.
• W1657151749 cites W2055326743 @default.
• W1657151749 cites W2061497773 @default.
• W1657151749 cites W2066578763 @default.
• W1657151749 cites W2071660572 @default.
• W1657151749 cites W2073877486 @default.
• W1657151749 cites W2090101179 @default.
• W1657151749 cites W2091197002 @default.
• W1657151749 cites W2092983150 @default.
• W1657151749 cites W2094045717 @default.
• W1657151749 cites W2108212934 @default.
• W1657151749 cites W2115235249 @default.
• W1657151749 cites W2115432748 @default.
• W1657151749 cites W2123182031 @default.
• W1657151749 cites W2134153999 @default.
• W1657151749 cites W2135628593 @default.
• W1657151749 cites W2138298815 @default.
• W1657151749 cites W2139560403 @default.
• W1657151749 cites W2144816857 @default.
• W1657151749 cites W2159737038 @default.
• W1657151749 cites W2163579301 @default.
• W1657151749 cites W2168558795 @default.
• W1657151749 cites W2319471468 @default.
• W1657151749 cites W4318373770 @default.
• W1657151749 cites W4318445484 @default.
• W1657151749 doi "https://doi.org/10.1016/j.euroneuro.2015.08.014" @default.
• W1657151749 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26342397" @default.
• W1657151749 hasPublicationYear "2015" @default.
• W1657151749 type Work @default.
• W1657151749 sameAs 1657151749 @default.
• W1657151749 citedByCount "31" @default.
• W1657151749 countsByYear W16571517492016 @default.
• W1657151749 countsByYear W16571517492017 @default.
• W1657151749 countsByYear W16571517492018 @default.
• W1657151749 countsByYear W16571517492019 @default.
• W1657151749 countsByYear W16571517492020 @default.
• W1657151749 countsByYear W16571517492021 @default.
• W1657151749 countsByYear W16571517492022 @default.
• W1657151749 countsByYear W16571517492023 @default.
• W1657151749 crossrefType "journal-article" @default.
• W1657151749 hasAuthorship W1657151749A5035038268 @default.
• W1657151749 hasAuthorship W1657151749A5043345480 @default.
• W1657151749 hasAuthorship W1657151749A5049561335 @default.
• W1657151749 hasAuthorship W1657151749A5087489056 @default.
• W1657151749 hasConcept C118552586 @default.
• W1657151749 hasConcept C126322002 @default.
• W1657151749 hasConcept C138885662 @default.
• W1657151749 hasConcept C164622146 @default.
• W1657151749 hasConcept C207103383 @default.
• W1657151749 hasConcept C2777669559 @default.
• W1657151749 hasConcept C2779134260 @default.
• W1657151749 hasConcept C2779177272 @default.
• W1657151749 hasConcept C2779483572 @default.
• W1657151749 hasConcept C2781081902 @default.
• W1657151749 hasConcept C2781161787 @default.
• W1657151749 hasConcept C2908647359 @default.
• W1657151749 hasConcept C41895202 @default.
• W1657151749 hasConcept C44249647 @default.
• W1657151749 hasConcept C50382708 @default.
• W1657151749 hasConcept C71924100 @default.
• W1657151749 hasConcept C98274493 @default.
• W1657151749 hasConcept C99454951 @default.
• W1657151749 hasConceptScore W1657151749C118552586 @default.
• W1657151749 hasConceptScore W1657151749C126322002 @default.
• W1657151749 hasConceptScore W1657151749C138885662 @default.
• W1657151749 hasConceptScore W1657151749C164622146 @default.
• W1657151749 hasConceptScore W1657151749C207103383 @default.
• W1657151749 hasConceptScore W1657151749C2777669559 @default.
• W1657151749 hasConceptScore W1657151749C2779134260 @default.
• W1657151749 hasConceptScore W1657151749C2779177272 @default.
• W1657151749 hasConceptScore W1657151749C2779483572 @default.
• W1657151749 hasConceptScore W1657151749C2781081902 @default.
• W1657151749 hasConceptScore W1657151749C2781161787 @default.

• next