Matches in SemOpenAlex for { <https://semopenalex.org/work/W16572607> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W16572607 endingPage "1053" @default.
- W16572607 startingPage "1047" @default.
- W16572607 abstract "Chlorpyrifos, an organophosphate insecticide of phosphorothioate group was orally administered to male rats at the doses of 3, 6 and 9 mg kg(-1) d(-1) for 90 days. Animals exposed to high dose (9 mg kg(-1) d(-1)) showed signs of toxicity including piloerection, diarrhoea, nose and eye bleeding, reduced body weight and death of animals. Organ weight ratio of different vital organs did not show any change except increase in adrenal weight and decrease in the weight of testes in animals of high dose (9 mg kg(-1) d(-1)). A dose dependent inhibition of acetylcholinesterase (AChE) activity in RBC (22-60%) and brain (7-52%) was observed. Microscopic examination of different tissues of male rats showed minor histopathological changes in brain, liver testis, epididymis and adrenal. The activity of testicular enzymes SDH, G-6-PDH and testicular content of sialic acid and cholesterol were found increased in animals of high dose (9 mg kg(-1) d(-1)). There was decrease in RBC counts and levels of hemoglobin (Hb) and hematocrit (HCT) with increase in WBC counts. While, total protein was decreased significantly at all the dose levels in testes and epididymis, glucose level showed a significant decrease at high dose. A dose dependent increase was observed in the level of serum triglycerides. There was no change in sperm motility and sperm morphology at any dose level except a decrease in sperm counts (114.1 x 10(6) g(-1) in high dose for group against 158.9 x 10(6) g(-1) controls). It is suggested that chlorpyrifos at 9 mg/kg/d dose for 90 days has caused toxicological changes along with mild testicular and spermatotoxic effects in male rats." @default.
- W16572607 created "2016-06-24" @default.
- W16572607 creator A5005845639 @default.
- W16572607 creator A5018903300 @default.
- W16572607 creator A5037021649 @default.
- W16572607 date "2009-11-01" @default.
- W16572607 modified "2023-10-02" @default.
- W16572607 title "Assessment of chlorpyrifos toxicity on certain organs in rat, Rattus norvegicus." @default.
- W16572607 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20329403" @default.
- W16572607 hasPublicationYear "2009" @default.
- W16572607 type Work @default.
- W16572607 sameAs 16572607 @default.
- W16572607 citedByCount "19" @default.
- W16572607 countsByYear W165726072012 @default.
- W16572607 countsByYear W165726072013 @default.
- W16572607 countsByYear W165726072014 @default.
- W16572607 countsByYear W165726072015 @default.
- W16572607 countsByYear W165726072016 @default.
- W16572607 countsByYear W165726072017 @default.
- W16572607 countsByYear W165726072018 @default.
- W16572607 countsByYear W165726072019 @default.
- W16572607 countsByYear W165726072020 @default.
- W16572607 countsByYear W165726072021 @default.
- W16572607 countsByYear W165726072022 @default.
- W16572607 crossrefType "journal-article" @default.
- W16572607 hasAuthorship W16572607A5005845639 @default.
- W16572607 hasAuthorship W16572607A5018903300 @default.
- W16572607 hasAuthorship W16572607A5037021649 @default.
- W16572607 hasConcept C126322002 @default.
- W16572607 hasConcept C134018914 @default.
- W16572607 hasConcept C161176658 @default.
- W16572607 hasConcept C16685009 @default.
- W16572607 hasConcept C167552308 @default.
- W16572607 hasConcept C181199279 @default.
- W16572607 hasConcept C2776588719 @default.
- W16572607 hasConcept C2777318727 @default.
- W16572607 hasConcept C2777632594 @default.
- W16572607 hasConcept C2778816929 @default.
- W16572607 hasConcept C2778917026 @default.
- W16572607 hasConcept C2779059548 @default.
- W16572607 hasConcept C2780959883 @default.
- W16572607 hasConcept C2781087480 @default.
- W16572607 hasConcept C2781254305 @default.
- W16572607 hasConcept C29730261 @default.
- W16572607 hasConcept C55493867 @default.
- W16572607 hasConcept C6557445 @default.
- W16572607 hasConcept C71924100 @default.
- W16572607 hasConcept C86803240 @default.
- W16572607 hasConceptScore W16572607C126322002 @default.
- W16572607 hasConceptScore W16572607C134018914 @default.
- W16572607 hasConceptScore W16572607C161176658 @default.
- W16572607 hasConceptScore W16572607C16685009 @default.
- W16572607 hasConceptScore W16572607C167552308 @default.
- W16572607 hasConceptScore W16572607C181199279 @default.
- W16572607 hasConceptScore W16572607C2776588719 @default.
- W16572607 hasConceptScore W16572607C2777318727 @default.
- W16572607 hasConceptScore W16572607C2777632594 @default.
- W16572607 hasConceptScore W16572607C2778816929 @default.
- W16572607 hasConceptScore W16572607C2778917026 @default.
- W16572607 hasConceptScore W16572607C2779059548 @default.
- W16572607 hasConceptScore W16572607C2780959883 @default.
- W16572607 hasConceptScore W16572607C2781087480 @default.
- W16572607 hasConceptScore W16572607C2781254305 @default.
- W16572607 hasConceptScore W16572607C29730261 @default.
- W16572607 hasConceptScore W16572607C55493867 @default.
- W16572607 hasConceptScore W16572607C6557445 @default.
- W16572607 hasConceptScore W16572607C71924100 @default.
- W16572607 hasConceptScore W16572607C86803240 @default.
- W16572607 hasIssue "6" @default.
- W16572607 hasLocation W165726071 @default.
- W16572607 hasLocation W165726072 @default.
- W16572607 hasOpenAccess W16572607 @default.
- W16572607 hasPrimaryLocation W165726071 @default.
- W16572607 hasRelatedWork W1965230909 @default.
- W16572607 hasRelatedWork W1971048984 @default.
- W16572607 hasRelatedWork W1977582803 @default.
- W16572607 hasRelatedWork W1982026267 @default.
- W16572607 hasRelatedWork W1999906380 @default.
- W16572607 hasRelatedWork W2000332894 @default.
- W16572607 hasRelatedWork W2004391012 @default.
- W16572607 hasRelatedWork W2012326229 @default.
- W16572607 hasRelatedWork W2027921405 @default.
- W16572607 hasRelatedWork W2033721784 @default.
- W16572607 hasRelatedWork W2036651930 @default.
- W16572607 hasRelatedWork W2044792915 @default.
- W16572607 hasRelatedWork W2059140737 @default.
- W16572607 hasRelatedWork W2060055730 @default.
- W16572607 hasRelatedWork W2080700268 @default.
- W16572607 hasRelatedWork W2098083421 @default.
- W16572607 hasRelatedWork W2141130068 @default.
- W16572607 hasRelatedWork W2182147096 @default.
- W16572607 hasRelatedWork W2187542898 @default.
- W16572607 hasRelatedWork W2436679327 @default.
- W16572607 hasVolume "30" @default.
- W16572607 isParatext "false" @default.
- W16572607 isRetracted "false" @default.
- W16572607 magId "16572607" @default.
- W16572607 workType "article" @default.