Matches in SemOpenAlex for { <https://semopenalex.org/work/W1659741523> ?p ?o ?g. }
- W1659741523 endingPage "3406" @default.
- W1659741523 startingPage "3397" @default.
- W1659741523 abstract "BACKGROUND: Androgen deprivation therapy (ADT) improves prostate cancer outcomes in specific clinical settings, but is associated with adverse effects, including cardiac complications and possibly thromboembolic complications. The objective of this study was to estimate the impact of ADT on thromboembolic events (TEs) in a population-based cohort. METHODS: In the linked Surveillance, Epidemiology and End Results–Medicare database, we identified men older than 65 who were diagnosed with nonmetastatic prostate cancer between 1999 and 2005. Medical or surgical ADT was identified by Medicare claims for gonadotropin-releasing hormone agonists or bilateral orchiectomy at any time following diagnosis. TEs included deep venous thrombosis, pulmonary embolism, and arterial embolism. The impact of ADT on the risk of any TE and on total number of events was estimated, controlling for patient and tumor characteristics. RESULTS: Of 154,611 patients with prostate cancer, 58,466 (38%) received ADT. During a median follow-up of 52 months, 15,950 men had at least 1 TE, including 8829 (55%) who had ADT and 7121 (45%) with no ADT. ADT was associated with increased risk of a TE (adjusted hazard ratio = 1.56; 95% confidence interval, 1.50-1.61; P < .0001), and duration of ADT was associated with the total number of events (P < .0001). CONCLUSIONS: In this population-based cohort, ADT was associated with increased risk of a TE, and longer durations of ADT were associated with more TEs. Men with intermediate- and low-risk prostate cancer should be assessed for TE risk factors before starting ADT and counseled regarding the risks and benefits of this therapy. Cancer 2011. © 2011 American Cancer Society." @default.
- W1659741523 created "2016-06-24" @default.
- W1659741523 creator A5012224683 @default.
- W1659741523 creator A5014513524 @default.
- W1659741523 creator A5016448202 @default.
- W1659741523 creator A5017288060 @default.
- W1659741523 creator A5023233762 @default.
- W1659741523 creator A5030594142 @default.
- W1659741523 creator A5056866163 @default.
- W1659741523 creator A5063707394 @default.
- W1659741523 creator A5085293654 @default.
- W1659741523 date "2011-11-09" @default.
- W1659741523 modified "2023-10-16" @default.
- W1659741523 title "Androgen deprivation and thromboembolic events in men with prostate cancer" @default.
- W1659741523 cites W1486671141 @default.
- W1659741523 cites W1576779400 @default.
- W1659741523 cites W1970232130 @default.
- W1659741523 cites W1972939339 @default.
- W1659741523 cites W1980224053 @default.
- W1659741523 cites W1985587689 @default.
- W1659741523 cites W1999668293 @default.
- W1659741523 cites W2008549629 @default.
- W1659741523 cites W2011966376 @default.
- W1659741523 cites W2013136992 @default.
- W1659741523 cites W2017954678 @default.
- W1659741523 cites W2020120231 @default.
- W1659741523 cites W2034934074 @default.
- W1659741523 cites W2037993667 @default.
- W1659741523 cites W2054324054 @default.
- W1659741523 cites W2055671944 @default.
- W1659741523 cites W2076124278 @default.
- W1659741523 cites W2085368059 @default.
- W1659741523 cites W2089396531 @default.
- W1659741523 cites W2091952316 @default.
- W1659741523 cites W2098998490 @default.
- W1659741523 cites W2105310697 @default.
- W1659741523 cites W2115201106 @default.
- W1659741523 cites W2120993630 @default.
- W1659741523 cites W2128365260 @default.
- W1659741523 cites W2129509910 @default.
- W1659741523 cites W2134766389 @default.
- W1659741523 cites W2135033329 @default.
- W1659741523 cites W2140905531 @default.
- W1659741523 cites W2142359566 @default.
- W1659741523 cites W2148386014 @default.
- W1659741523 cites W2157358083 @default.
- W1659741523 cites W2158734599 @default.
- W1659741523 cites W2161964583 @default.
- W1659741523 cites W2165990809 @default.
- W1659741523 cites W2237319448 @default.
- W1659741523 cites W2275737843 @default.
- W1659741523 cites W2313284959 @default.
- W1659741523 cites W2490019007 @default.
- W1659741523 cites W4249976229 @default.
- W1659741523 cites W4295773257 @default.
- W1659741523 cites W4376595850 @default.
- W1659741523 doi "https://doi.org/10.1002/cncr.26623" @default.
- W1659741523 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3678973" @default.
- W1659741523 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22072494" @default.
- W1659741523 hasPublicationYear "2011" @default.
- W1659741523 type Work @default.
- W1659741523 sameAs 1659741523 @default.
- W1659741523 citedByCount "71" @default.
- W1659741523 countsByYear W16597415232012 @default.
- W1659741523 countsByYear W16597415232013 @default.
- W1659741523 countsByYear W16597415232014 @default.
- W1659741523 countsByYear W16597415232015 @default.
- W1659741523 countsByYear W16597415232016 @default.
- W1659741523 countsByYear W16597415232017 @default.
- W1659741523 countsByYear W16597415232018 @default.
- W1659741523 countsByYear W16597415232019 @default.
- W1659741523 countsByYear W16597415232020 @default.
- W1659741523 countsByYear W16597415232021 @default.
- W1659741523 countsByYear W16597415232022 @default.
- W1659741523 countsByYear W16597415232023 @default.
- W1659741523 crossrefType "journal-article" @default.
- W1659741523 hasAuthorship W1659741523A5012224683 @default.
- W1659741523 hasAuthorship W1659741523A5014513524 @default.
- W1659741523 hasAuthorship W1659741523A5016448202 @default.
- W1659741523 hasAuthorship W1659741523A5017288060 @default.
- W1659741523 hasAuthorship W1659741523A5023233762 @default.
- W1659741523 hasAuthorship W1659741523A5030594142 @default.
- W1659741523 hasAuthorship W1659741523A5056866163 @default.
- W1659741523 hasAuthorship W1659741523A5063707394 @default.
- W1659741523 hasAuthorship W1659741523A5085293654 @default.
- W1659741523 hasBestOaLocation W16597415231 @default.
- W1659741523 hasConcept C121608353 @default.
- W1659741523 hasConcept C126322002 @default.
- W1659741523 hasConcept C126894567 @default.
- W1659741523 hasConcept C143998085 @default.
- W1659741523 hasConcept C207103383 @default.
- W1659741523 hasConcept C2776265017 @default.
- W1659741523 hasConcept C2777899217 @default.
- W1659741523 hasConcept C2780011451 @default.
- W1659741523 hasConcept C2780192828 @default.
- W1659741523 hasConcept C2780868729 @default.
- W1659741523 hasConcept C2908647359 @default.
- W1659741523 hasConcept C29456083 @default.