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- W166020462 abstract "The aim of evidence-based medicine (EBM) is to inform clinical practice in the light of all available evidence. Systematic review, in which one rigorously synthesizes all of the published literature relevant to a precisely formulated clinical question, is the foundation of EBM. Creating such syntheses involves identifying, extracting and combining reliable pieces of evidence from published articles. Systematic reviews are increasingly used to inform decisions at all levels of health care, from bedside individualized care to policy-making. They have gained wide acceptance as a practical way to provide reliable and comprehensive syntheses of the medical evidence base. But producing and maintaining such reviews is becoming increasingly onerous due to the exponential expansion of the biomedical literature: as the amount of published evidence increases, so too does the labor required to synthesize it. Moreover, higher standards for review methods have further increased the labor involved in conducting systematic reviews, exacerbating the problems caused by information overload. This chapter provides a basic introduction to systematic review and meta-analysis methods; here we focus on methods for providing the evidence base for decision support, and also the potential for medical informatics to facilitate and optimize the conduct and maintenance of evidence syntheses." @default.
- W166020462 created "2016-06-24" @default.
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- W166020462 date "2014-01-01" @default.
- W166020462 modified "2023-10-10" @default.
- W166020462 title "Modernizing Evidence Synthesis for Evidence-Based Medicine" @default.
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- W166020462 doi "https://doi.org/10.1016/b978-0-12-398476-0.00012-9" @default.
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