FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1662003105> ?p ?o ?g. }

• W1662003105 endingPage "n/a" @default.
• W1662003105 startingPage "n/a" @default.
• W1662003105 abstract "Major issues faced with the use of today's skin grafts are infection, scar tissue formation, insufficient keratinocyte (or skin producing cells) proliferation and high production costs. To overcome these limitations, we propose here for the first time, a nanofeatured poly(lactide-co-glycolide) (PLGA) membrane as a next generation antibacterial skin graft material. An alkaline surface treatment method was used to create random nanofeatures on PLGA membranes where sodium hydroxide (NaOH) concentration and exposure times were altered to control surface morphology. Most significantly, and without the use of antibiotics, results showed a decrease in Staphylococcus aureus (a dangerous pathogen infecting skin grafts) growth for up to ∼40% after 2 days of culture on nanofeatured PLGA membranes compared to untreated controls. Results also showed that while bacteria growth was stunted, mammalian cell growth was not. Specifically, cell culture results showed an increase in human epidermal keratinocyte density, while the density of scar tissue forming human dermal fibroblasts, did not change on nanofeatured PLGA surfaces compared to the untreated controls after 3 days of culture. These findings indicate that the alkaline treatment of PLGA membranes is a promising quick and effective manner to limit scar tissue formation and bacterial invasion while increasing skin cell proliferation for improving numerous wound-healing applications. © 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 102A: 4598–4608, 2014." @default.
• W1662003105 created "2016-06-24" @default.
• W1662003105 creator A5007254102 @default.
• W1662003105 creator A5019941350 @default.
• W1662003105 creator A5023950150 @default.
• W1662003105 creator A5047022549 @default.
• W1662003105 creator A5076201188 @default.
• W1662003105 creator A5078615923 @default.
• W1662003105 date "2014-03-01" @default.
• W1662003105 modified "2023-10-03" @default.
• W1662003105 title "Nanostructured anti-bacterial poly-lactic-co-glycolic acid films for skin tissue engineering applications" @default.
• W1662003105 cites W1909975518 @default.
• W1662003105 cites W1976467027 @default.
• W1662003105 cites W1978670963 @default.
• W1662003105 cites W1981280006 @default.
• W1662003105 cites W1996734513 @default.
• W1662003105 cites W2007414660 @default.
• W1662003105 cites W2008827477 @default.
• W1662003105 cites W2017291345 @default.
• W1662003105 cites W2023428109 @default.
• W1662003105 cites W2029664061 @default.
• W1662003105 cites W2036110914 @default.
• W1662003105 cites W2042950683 @default.
• W1662003105 cites W2074264405 @default.
• W1662003105 cites W2078958131 @default.
• W1662003105 cites W2089413243 @default.
• W1662003105 cites W2092162598 @default.
• W1662003105 cites W2134352129 @default.
• W1662003105 cites W2135298847 @default.
• W1662003105 cites W2139510804 @default.
• W1662003105 cites W2162036259 @default.
• W1662003105 cites W2162061971 @default.
• W1662003105 cites W2253841253 @default.
• W1662003105 doi "https://doi.org/10.1002/jbm.a.35141" @default.
• W1662003105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24677536" @default.
• W1662003105 hasPublicationYear "2014" @default.
• W1662003105 type Work @default.
• W1662003105 sameAs 1662003105 @default.
• W1662003105 citedByCount "5" @default.
• W1662003105 countsByYear W16620031052015 @default.
• W1662003105 countsByYear W16620031052017 @default.
• W1662003105 countsByYear W16620031052018 @default.
• W1662003105 crossrefType "journal-article" @default.
• W1662003105 hasAuthorship W1662003105A5007254102 @default.
• W1662003105 hasAuthorship W1662003105A5019941350 @default.
• W1662003105 hasAuthorship W1662003105A5023950150 @default.
• W1662003105 hasAuthorship W1662003105A5047022549 @default.
• W1662003105 hasAuthorship W1662003105A5076201188 @default.
• W1662003105 hasAuthorship W1662003105A5078615923 @default.
• W1662003105 hasConcept C136229726 @default.
• W1662003105 hasConcept C141071460 @default.
• W1662003105 hasConcept C155672457 @default.
• W1662003105 hasConcept C171250308 @default.
• W1662003105 hasConcept C185592680 @default.
• W1662003105 hasConcept C192562407 @default.
• W1662003105 hasConcept C2775920511 @default.
• W1662003105 hasConcept C2777074287 @default.
• W1662003105 hasConcept C2777459323 @default.
• W1662003105 hasConcept C2780165375 @default.
• W1662003105 hasConcept C2780269544 @default.
• W1662003105 hasConcept C2780472526 @default.
• W1662003105 hasConcept C41625074 @default.
• W1662003105 hasConcept C49892992 @default.
• W1662003105 hasConcept C523546767 @default.
• W1662003105 hasConcept C54355233 @default.
• W1662003105 hasConcept C55493867 @default.
• W1662003105 hasConcept C62112901 @default.
• W1662003105 hasConcept C71924100 @default.
• W1662003105 hasConcept C81885089 @default.
• W1662003105 hasConcept C86803240 @default.
• W1662003105 hasConceptScore W1662003105C136229726 @default.
• W1662003105 hasConceptScore W1662003105C141071460 @default.
• W1662003105 hasConceptScore W1662003105C155672457 @default.
• W1662003105 hasConceptScore W1662003105C171250308 @default.
• W1662003105 hasConceptScore W1662003105C185592680 @default.
• W1662003105 hasConceptScore W1662003105C192562407 @default.
• W1662003105 hasConceptScore W1662003105C2775920511 @default.
• W1662003105 hasConceptScore W1662003105C2777074287 @default.
• W1662003105 hasConceptScore W1662003105C2777459323 @default.
• W1662003105 hasConceptScore W1662003105C2780165375 @default.
• W1662003105 hasConceptScore W1662003105C2780269544 @default.
• W1662003105 hasConceptScore W1662003105C2780472526 @default.
• W1662003105 hasConceptScore W1662003105C41625074 @default.
• W1662003105 hasConceptScore W1662003105C49892992 @default.
• W1662003105 hasConceptScore W1662003105C523546767 @default.
• W1662003105 hasConceptScore W1662003105C54355233 @default.
• W1662003105 hasConceptScore W1662003105C55493867 @default.
• W1662003105 hasConceptScore W1662003105C62112901 @default.
• W1662003105 hasConceptScore W1662003105C71924100 @default.
• W1662003105 hasConceptScore W1662003105C81885089 @default.
• W1662003105 hasConceptScore W1662003105C86803240 @default.
• W1662003105 hasLocation W16620031051 @default.
• W1662003105 hasLocation W16620031052 @default.
• W1662003105 hasOpenAccess W1662003105 @default.
• W1662003105 hasPrimaryLocation W16620031051 @default.
• W1662003105 hasRelatedWork W1662003105 @default.
• W1662003105 hasRelatedWork W1969666931 @default.
• W1662003105 hasRelatedWork W202277335 @default.

• next