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- W16626727 abstract "Vitamin D deficiency is common in South Asia, but the causes are unclear. Particulate air pollution interferes with ultraviolet (UV) irradiation of the earth surface, but the effect of UV-absorbing aerosols on vitamin D status is unknown. Associations among vitamin D status (serum 25-hydroxyvitamin D, [25(OH)D]), UV radiation exposure and UV-absorbing aerosols in Dhaka were explored based on observations of 34 non-pregnant and 13 pregnant women in July-Oct 2009, and 28 pregnant women in Feb 2010 (N=75). Average [25(OH)D] was lower in winter vs. summer/fall; among the pregnant women, mean [25(OH)D] was 12 nmol/L lower in Feb vs. Aug-Oct (95% CI, 1 – 22 nmol/L). Seasonal differences in [25(OH)D] could be largely explained by variations in personal UV exposure estimated using polysulphone (PS) badges worn on the shoulder, averaged over 2–3 days within ~2 months of [25(OH)D] assessment (N=72). UV exposure by PS dosimetry and [25(OH)D] were both inversely associated with the estimated UV aerosol index (UVAI) for Dhaka, based on satellite-generated data downloaded from an on-line NASA database (OMI/Aura). The UVAI peaked in early spring (before the monsoon season), when average UV exposures by PS dosimetry were lowest. These preliminary observations suggest that UV-absorbing aerosols may have important effects on UV-induced cutaneous vitamin D synthesis in South Asia and merit further research. Grant Funding Source: Center for Global Health, Johns Hopkins University; Department of International Health, Johns Hopkins Bloomberg School of Public Health" @default.
- W16626727 created "2016-06-24" @default.
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- W16626727 date "2011-04-01" @default.
- W16626727 modified "2023-09-27" @default.
- W16626727 title "Seasonal variations in vitamin D status in Bangladesh: a preliminary look at the potential role of aerosol pollution" @default.
- W16626727 doi "https://doi.org/10.1096/fasebj.25.1_supplement.996.19" @default.
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