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- W166307528 abstract "An oxygen gradient exists from atmosphere to mitochondria (the oxygen cascade) (Fig. 1). Over 90% of oxygen utilized by the body is consumed by a single enzyme complex, cytochrome oxidase (Complex IV), which is situated at the end of the mitochondrial electron transport chain. Oxygen is thus the terminal electron acceptor and is reduced to water. The electron transport chain accepts electrons from the citric acid cycle and as these are passed down the chain, H+ ions cross the inner mitochondrial membrane, generating an electrical gradient (‘proton motive force’) which provides the energy to drive phosphorylation of adenosine diphosphate (ADP) to adenosine triphosphate (ATP) by the enzyme ATP-synthase (Fig. 2)." @default.
- W166307528 created "2016-06-24" @default.
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- W166307528 date "1999-01-01" @default.
- W166307528 modified "2023-09-24" @default.
- W166307528 title "Coping with Hypoxia" @default.
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- W166307528 doi "https://doi.org/10.1007/978-3-662-13453-5_33" @default.
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