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• W1663226981 endingPage "2575" @default.
• W1663226981 startingPage "2569" @default.
• W1663226981 abstract "DNA helicase II, the product of the uvrD gene, has been implicated in DNA repair, replication, and recombination. Because the phenotypes of individual uvrD alleles vary significantly, we constructed deletion-insertion mutations in the uvrD gene to determine the phenotype of cells lacking DNA helicase II. Deletion mutants completely lacking the protein, as well as one which contains a truncated protein retaining the ATP-binding site, remained viable. However, they were sensitive to UV light and exhibited elevated levels of homologous recombination and spontaneous mutagenesis. In addition, mutations mapping in or near rep which allow construction of rep uvrD double mutants at a high frequency were isolated." @default.
• W1663226981 created "2016-06-24" @default.
• W1663226981 creator A5010896477 @default.
• W1663226981 creator A5058481221 @default.
• W1663226981 date "1991-04-01" @default.
• W1663226981 modified "2023-09-25" @default.
• W1663226981 title "Construction and analysis of deletions in the structural gene (uvrD) for DNA helicase II of Escherichia coli" @default.
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• W1663226981 doi "https://doi.org/10.1128/jb.173.8.2569-2575.1991" @default.
• W1663226981 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/207822" @default.
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