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- W1667383989 abstract "Efficacy of a pH-dependent controlled-release mesalazine based on clinical and endoscopic assessment for ulcerative colitis: a retrospective cohort study Satohiro Matsumoto, Yukio Yoshida Department of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama, Japan Background: We conducted a retrospective cohort study to clinically and endoscopically assess the efficacy of delayed-release mesalazine for ulcerative colitis.Methods: The study included 104 ulcerative colitis patients (52 men, 52 women) initiated on treatment with delayed-release mesalazine between 2009 and 2012. The clinical symptoms at months 0, 1, and 12 were scored using the clinical activity index. An endoscopic index was also used to determine disease activity in 72 patients who underwent total colonoscopy before and after mesalazine treatment.Results: The clinical activity index at months 0, 1, and 12 were 4.6±2.8, 3.4±1.8, and 2.8±1.4, respectively, decreasing with time after the start of mesalazine treatment (P" @default.
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- W1667383989 date "2015-07-01" @default.
- W1667383989 modified "2023-09-25" @default.
- W1667383989 title "Efficacy of a pH-dependent controlled-release mesalazine based on clinical and endoscopic assessment for ulcerative colitis: a retrospective cohort study" @default.
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- W1667383989 doi "https://doi.org/10.2147/ceg.s86528" @default.
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