FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1669701013> ?p ?o ?g. }

• W1669701013 endingPage "289" @default.
• W1669701013 startingPage "283" @default.
• W1669701013 abstract "A 4.3-kb EcoRI fragment from a Lactococcus lactis genomic library alleviates the methyl methanesulfonate, mitomycin C, and UV sensitivities of an Escherichia coli recA mutant (M. Novel, X. F. Huang, and G. Novel, FEMS Microbiol. Lett. 72:309-314, 1990). It complements recA1 and delta recA mutations but not recA13. Three proteins (with molecular masses of 20, 35, and 23 kDa) were produced from this fragment in a T7-directed system, and three corresponding genes were detected by DNA sequencing, namely, ISS1CH;lacX, which is the distal gene of the lac operon; and a third open reading frame, named lacN, which encodes 211 amino acids. Mutations produced in either lacX or in lacN resulted in the loss of the resistance to DNA-damaging agents. Thus, these two genes appeared to be involved in this activity. Introduction of pUCB214 carrying the 4.3-kb fragment into a lexA+ delta recA306 sfiA::lacZ strain resulted in UV-inducible synthesis of beta-galactosidase. A uvrA strain or a lexA (Ind-) strain containing pUCB214 did not support any DNA repair. However, a lexA (Def-) strain carrying pUCB214 could partly repair UV damage. We discuss possible targets for LacX and LacN products, and we speculate that LacX and LacN may constitute a two-component regulatory system that is able to respond to SOS signals, and then to act in the SOS response, bypassing the RecA-activated function." @default.
• W1669701013 created "2016-06-24" @default.
• W1669701013 creator A5000550485 @default.
• W1669701013 creator A5016435989 @default.
• W1669701013 creator A5017820327 @default.
• W1669701013 creator A5064934122 @default.
• W1669701013 date "1995-01-01" @default.
• W1669701013 modified "2023-09-27" @default.
• W1669701013 title "Two Lactococcus lactis genes, including lacX, cooperate to trigger an SOS response in a recA-negative background" @default.
• W1669701013 cites W1490028929 @default.
• W1669701013 cites W1496520005 @default.
• W1669701013 cites W1510612702 @default.
• W1669701013 cites W1513001859 @default.
• W1669701013 cites W1532012911 @default.
• W1669701013 cites W1554531066 @default.
• W1669701013 cites W1557362760 @default.
• W1669701013 cites W1565544659 @default.
• W1669701013 cites W1611916174 @default.
• W1669701013 cites W1621450368 @default.
• W1669701013 cites W1625936880 @default.
• W1669701013 cites W1641454687 @default.
• W1669701013 cites W1693850275 @default.
• W1669701013 cites W1773402115 @default.
• W1669701013 cites W1825541953 @default.
• W1669701013 cites W1869928545 @default.
• W1669701013 cites W1882839676 @default.
• W1669701013 cites W1905982714 @default.
• W1669701013 cites W1939432223 @default.
• W1669701013 cites W1952814327 @default.
• W1669701013 cites W1965676881 @default.
• W1669701013 cites W1982521068 @default.
• W1669701013 cites W1989982095 @default.
• W1669701013 cites W1996693838 @default.
• W1669701013 cites W2034816601 @default.
• W1669701013 cites W2038757378 @default.
• W1669701013 cites W2043972155 @default.
• W1669701013 cites W2064395970 @default.
• W1669701013 cites W2068518785 @default.
• W1669701013 cites W2076875540 @default.
• W1669701013 cites W2125935184 @default.
• W1669701013 cites W2138270253 @default.
• W1669701013 cites W2139325759 @default.
• W1669701013 cites W2143504908 @default.
• W1669701013 cites W2150989483 @default.
• W1669701013 cites W2151546745 @default.
• W1669701013 cites W2153563795 @default.
• W1669701013 cites W2163037357 @default.
• W1669701013 cites W2169175266 @default.
• W1669701013 cites W2173962436 @default.
• W1669701013 cites W2321041782 @default.
• W1669701013 cites W2416238412 @default.
• W1669701013 cites W4254983419 @default.
• W1669701013 cites W2005675069 @default.
• W1669701013 doi "https://doi.org/10.1128/jb.177.2.283-289.1995" @default.
• W1669701013 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/176589" @default.
• W1669701013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7814316" @default.
• W1669701013 hasPublicationYear "1995" @default.
• W1669701013 type Work @default.
• W1669701013 sameAs 1669701013 @default.
• W1669701013 citedByCount "6" @default.
• W1669701013 crossrefType "journal-article" @default.
• W1669701013 hasAuthorship W1669701013A5000550485 @default.
• W1669701013 hasAuthorship W1669701013A5016435989 @default.
• W1669701013 hasAuthorship W1669701013A5017820327 @default.
• W1669701013 hasAuthorship W1669701013A5064934122 @default.
• W1669701013 hasBestOaLocation W16697010132 @default.
• W1669701013 hasConcept C104317684 @default.
• W1669701013 hasConcept C134935766 @default.
• W1669701013 hasConcept C143065580 @default.
• W1669701013 hasConcept C143425029 @default.
• W1669701013 hasConcept C150194340 @default.
• W1669701013 hasConcept C153911025 @default.
• W1669701013 hasConcept C158448853 @default.
• W1669701013 hasConcept C167625842 @default.
• W1669701013 hasConcept C203075996 @default.
• W1669701013 hasConcept C22744801 @default.
• W1669701013 hasConcept C2775920511 @default.
• W1669701013 hasConcept C2780011460 @default.
• W1669701013 hasConcept C2780852648 @default.
• W1669701013 hasConcept C413212 @default.
• W1669701013 hasConcept C47289529 @default.
• W1669701013 hasConcept C523546767 @default.
• W1669701013 hasConcept C54355233 @default.
• W1669701013 hasConcept C547475151 @default.
• W1669701013 hasConcept C552990157 @default.
• W1669701013 hasConcept C86803240 @default.
• W1669701013 hasConceptScore W1669701013C104317684 @default.
• W1669701013 hasConceptScore W1669701013C134935766 @default.
• W1669701013 hasConceptScore W1669701013C143065580 @default.
• W1669701013 hasConceptScore W1669701013C143425029 @default.
• W1669701013 hasConceptScore W1669701013C150194340 @default.
• W1669701013 hasConceptScore W1669701013C153911025 @default.
• W1669701013 hasConceptScore W1669701013C158448853 @default.
• W1669701013 hasConceptScore W1669701013C167625842 @default.
• W1669701013 hasConceptScore W1669701013C203075996 @default.
• W1669701013 hasConceptScore W1669701013C22744801 @default.
• W1669701013 hasConceptScore W1669701013C2775920511 @default.
• W1669701013 hasConceptScore W1669701013C2780011460 @default.

• next