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- W167032388 abstract "Evidence that retroviral-like transposable elements (RLEs) have played a significant role in regulatory evolution is summarized. It is proposed that suppressor genes are maintained in populations by natural selection as a defense against the unyielding mutational pressure presented by recurring RLE insertion mutants. The fortuitous long-term consequence of naturally occurring suppressor genes is the maintenance of hidden RLE mediated regulatory variation in populations. It is hypothesized that this hidden variation may be released during periods of forced inbreeding (e.g., genetic bottlenecks or founding events) resulting in the sudden emergence of new regulatory phenotypes." @default.
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- W167032388 date "1993-01-01" @default.
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- W167032388 title "Retroviral-like elements, suppressor genes and regulatory evolution" @default.
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- W167032388 doi "https://doi.org/10.1007/978-94-011-2028-9_5" @default.
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