FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1671306972> ?p ?o ?g. }

• W1671306972 endingPage "11" @default.
• W1671306972 startingPage "11" @default.
• W1671306972 abstract "Despite the medical importance of trichomoniasis, little is known about the genetic relatedness of Trichomonas vaginalis strains with similar biological characteristics. Furthermore, the distribution of endobionts such as mycoplasmas or Trichomonas vaginalis virus (TVV) in the T. vaginalis metapopulation is poorly characterised.We assayed the relationship between 20 strains of T. vaginalis from 8 countries using the Random Amplified Polymorphic DNA (RAPD) analysis with 27 random primers. The genealogical tree was constructed and its bootstrap values were computed using the program FreeTree. Using the permutation tail probability tests we found that the topology of the tree reflected both the pattern of resistance to metronidazole (the major anti-trichomonal drug) (p < 0.01) and the pattern of infection of strains by mycoplasmas (p < 0.05). However, the tree did not reflect pattern of virulence, geographic origin or infection by TVV. Despite low bootstrap support for many branches, the significant clustering of strains with similar drug susceptibility suggests that the tree approaches the true genealogy of strains. The clustering of mycoplasma positive strains may be an experimental artifact, caused by shared RAPD characters which are dependent on the presence of mycoplasma DNA.Our results confirmed both the suitability of the RAPD technique for genealogical studies in T. vaginalis and previous conclusions on the relatedness of metronidazol resistant strains. However, our studies indicate that testing analysed strains for the presence of endobionts and assessment of the robustness of tree topologies by bootstrap analysis seem to be obligatory steps in such analyses." @default.
• W1671306972 created "2016-06-24" @default.
• W1671306972 creator A5005884080 @default.
• W1671306972 creator A5008143610 @default.
• W1671306972 creator A5026263661 @default.
• W1671306972 creator A5030635992 @default.
• W1671306972 date "2001-01-01" @default.
• W1671306972 modified "2023-09-30" @default.
• W1671306972 cites W1487682906 @default.
• W1671306972 cites W1503431173 @default.
• W1671306972 cites W1574802261 @default.
• W1671306972 cites W1967386563 @default.
• W1671306972 cites W1969499296 @default.
• W1671306972 cites W1973218940 @default.
• W1671306972 cites W1982352583 @default.
• W1671306972 cites W1984390786 @default.
• W1671306972 cites W1988128159 @default.
• W1671306972 cites W1989157253 @default.
• W1671306972 cites W1994865247 @default.
• W1671306972 cites W2004687360 @default.
• W1671306972 cites W2008214584 @default.
• W1671306972 cites W2013090758 @default.
• W1671306972 cites W2019242166 @default.
• W1671306972 cites W2025657725 @default.
• W1671306972 cites W2027750147 @default.
• W1671306972 cites W2028476975 @default.
• W1671306972 cites W2047478018 @default.
• W1671306972 cites W2059353303 @default.
• W1671306972 cites W2069229663 @default.
• W1671306972 cites W2070588427 @default.
• W1671306972 cites W2076886235 @default.
• W1671306972 cites W2081059961 @default.
• W1671306972 cites W2086331614 @default.
• W1671306972 cites W2092983351 @default.
• W1671306972 cites W2097706568 @default.
• W1671306972 cites W2104645075 @default.
• W1671306972 cites W2115976270 @default.
• W1671306972 cites W2123668458 @default.
• W1671306972 cites W2148537294 @default.
• W1671306972 cites W2152732823 @default.
• W1671306972 cites W2154439575 @default.
• W1671306972 cites W2165496090 @default.
• W1671306972 cites W2171045827 @default.
• W1671306972 cites W2395567852 @default.
• W1671306972 cites W2395620807 @default.
• W1671306972 cites W2413209816 @default.
• W1671306972 cites W2429127832 @default.
• W1671306972 cites W927673673 @default.
• W1671306972 doi "https://doi.org/10.1186/1471-2148-1-11" @default.
• W1671306972 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/60492" @default.
• W1671306972 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11734059" @default.
• W1671306972 hasPublicationYear "2001" @default.
• W1671306972 type Work @default.
• W1671306972 sameAs 1671306972 @default.
• W1671306972 citedByCount "46" @default.
• W1671306972 countsByYear W16713069722012 @default.
• W1671306972 countsByYear W16713069722013 @default.
• W1671306972 countsByYear W16713069722014 @default.
• W1671306972 countsByYear W16713069722015 @default.
• W1671306972 countsByYear W16713069722016 @default.
• W1671306972 countsByYear W16713069722017 @default.
• W1671306972 countsByYear W16713069722018 @default.
• W1671306972 countsByYear W16713069722019 @default.
• W1671306972 countsByYear W16713069722020 @default.
• W1671306972 countsByYear W16713069722021 @default.
• W1671306972 countsByYear W16713069722022 @default.
• W1671306972 crossrefType "journal-article" @default.
• W1671306972 hasAuthorship W1671306972A5005884080 @default.
• W1671306972 hasAuthorship W1671306972A5008143610 @default.
• W1671306972 hasAuthorship W1671306972A5026263661 @default.
• W1671306972 hasAuthorship W1671306972A5030635992 @default.
• W1671306972 hasBestOaLocation W16713069721 @default.
• W1671306972 hasConcept C104317684 @default.
• W1671306972 hasConcept C144024400 @default.
• W1671306972 hasConcept C149923435 @default.
• W1671306972 hasConcept C193252679 @default.
• W1671306972 hasConcept C2778838687 @default.
• W1671306972 hasConcept C2781114625 @default.
• W1671306972 hasConcept C2908647359 @default.
• W1671306972 hasConcept C54355233 @default.
• W1671306972 hasConcept C81977670 @default.
• W1671306972 hasConcept C84623179 @default.
• W1671306972 hasConcept C86803240 @default.
• W1671306972 hasConceptScore W1671306972C104317684 @default.
• W1671306972 hasConceptScore W1671306972C144024400 @default.
• W1671306972 hasConceptScore W1671306972C149923435 @default.
• W1671306972 hasConceptScore W1671306972C193252679 @default.
• W1671306972 hasConceptScore W1671306972C2778838687 @default.
• W1671306972 hasConceptScore W1671306972C2781114625 @default.
• W1671306972 hasConceptScore W1671306972C2908647359 @default.
• W1671306972 hasConceptScore W1671306972C54355233 @default.
• W1671306972 hasConceptScore W1671306972C81977670 @default.
• W1671306972 hasConceptScore W1671306972C84623179 @default.
• W1671306972 hasConceptScore W1671306972C86803240 @default.
• W1671306972 hasIssue "1" @default.
• W1671306972 hasLocation W16713069721 @default.
• W1671306972 hasLocation W16713069722 @default.
• W1671306972 hasLocation W16713069723 @default.

• next