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- W1671348373 abstract "Hyaluronic acid is a component of the synovial fluid that plays an important role in articular homeostasis. It contributes to ensuring adequate lubrication, acts as a shock absorber for the transmission of loads over the articular surfaces, and endows the synovial fluid with anti- inflammatory and antinociceptive properties. In arthrosis, its molecular weight and concentration are reduced. This has lead to the idea that the administration of products derived from hyaluronic acid can restore the parameters cited to normal levels, which may have beneficial therapeutic effects. This treatment is known as viscosupplementation. The scientific community has received this idea with opinions ranging from skepticism to acceptance. More prospective, randomized, double-blind, controlled studies are needed before viscosupplementation with hyaluronic acid can be considered an effective treatment for knee arthrosis. For clinicians it is not enough that results be statistically significant, it is even more important that they be clinically relevant." @default.
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- W1671348373 date "2002-10-01" @default.
- W1671348373 modified "2023-09-26" @default.
- W1671348373 title "Aplicaciones clínicas y efectos terapéuticos de la viscosuplementación en la artrosis de rodilla" @default.
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