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- W1677374553 abstract "A high-performance liquid chromatography (HPLC) technique has been developed for determining impurities in the parent substance and tablets of tropoksin. Reliable separation of tropoksin and impurities was achieved on liquid chromatograph equipped with a spectrophotometric detector and a stainless steel column (250 × 4.6 mm) filled with C18 (5 μm) sorbent, in gradient elution mode. The detection limits for tropoksin and identified impurities were determined. It was found that the area under peak is a linear function of the tropoksin concentration in stock solutions in the range from 0.02% to 2%. The results were repeatedly reproduced in model mixtures, parent substance samples, and the various series of tropoksin tablets." @default.
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- W1677374553 date "2011-06-10" @default.
- W1677374553 modified "2023-09-25" @default.
- W1677374553 title "Разработка методики определения посторонних примесей в субстанции и таблетках тропоксина с помощью ВЭЖХ" @default.
- W1677374553 doi "https://doi.org/10.30906/0023-1134-2011-45-12-52-56" @default.
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