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- W1678398081 abstract "Publisher Summary This chapter focuses on the compounds that are known to lower plasma cholesterol by inhibiting cholesterol absorption in the small intestine, including plant sterols and stanols, soluble fibers, saponins, soy protein, phospholipids (SM and PC), and stearic acid. All of these compounds—except, perhaps, stearic acid—appear to exert their effects mainly by interfering with micellar solubilization of cholesterol within the intestinal lumen. This can be the result of displacing cholesterol from the micelle, binding or precipitating cholesterol, impeding the movement of cholesterol by forming a viscous matrix, inhibiting digestive enzymes, binding bile acids and decreasing their participation in micelle formation, or down regulating cholesterol transporters within the enterocyte. Stearic acid appears to work systemically by incorporating into hepatic and biliary phospholipids, which destabilizes micelles and reduces cholesterol solubility. These compounds are attractive to food and nutraceutical companies because, in most cases, they are regulated as foods and not drugs." @default.
- W1678398081 created "2016-06-24" @default.
- W1678398081 creator A5003509094 @default.
- W1678398081 creator A5067951429 @default.
- W1678398081 date "2006-01-01" @default.
- W1678398081 modified "2023-09-23" @default.
- W1678398081 title "Food Components that Reduce Cholesterol Absorption" @default.
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