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- W1680650526 abstract "Publisher Summary This chapter discusses sleep and neuromuscular disorders. There has been an increasing awareness in the medical community regarding sleep-disordered breathing (SDB) in patients with neuromuscular disorders since its initial recognition in bulbar poliomyelitis by Sarnoff and colleagues (1951), and in myotonic dystrophy by Benaim and Worster–Drought (1954). Most of the sleep disturbances in neuromuscular disorders are secondary to sleep-related respiratory dysfunction. Breathing is controlled during wakefulness and sleep by two independent and separate systems—the metabolic or automatic, and the voluntary or behavioral systems. During wakefulness both systems operate but during sleep, breathing is entirely dependent on the metabolic or automatic control system in the medulla. Respiratory rhythmogenesis depends on tonic input from the peripheral and central structures converging on medullary neurons. The parasympathetic vagal afferents, the carotid and aortic body peripheral chemoreceptors, the central medullary chemoreceptors, the supra medullary, and reticular activating systems all influence the medullary respiratory neurons in maintaining respiratory homeostasis." @default.
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- W1680650526 date "2005-01-01" @default.
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- W1680650526 title "Chapter 17 Sleep and neuromuscular disorders" @default.
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- W1680650526 doi "https://doi.org/10.1016/s1567-4231(09)70042-5" @default.
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