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- W1681969670 abstract "Regulation of gene expression is mainly conducted by transcription factors (TFs) binding to upstream regions of their target genes (Targets). Many algorithms have been developed to extract such regulatory relationships between TFs and Targets from time series expression profiles. Here we focus our attention on the time delay of TF expression and its Targets expression, which may not be uniform because of the fluctuation of regulatory interactions. We analyzed time series expression profiles in yeast cell cycles and observed such regulatory delays within known pairs of TFs and Targets, providing the evidence that the distribution of such delays is not uniform." @default.
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- W1681969670 date "2003-01-01" @default.
- W1681969670 modified "2023-09-23" @default.
- W1681969670 title "Comprehensive Analysis of Delay in Transcriptional Regulation Using Expression Profiles" @default.
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- W1681969670 doi "https://doi.org/10.11234/gi1990.14.302" @default.
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