FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1683142258> ?p ?o ?g. }

• W1683142258 abstract "A public tuberculosis (TB) referral hospital in KwaZulu-Natal, South Africa.To present treatment outcomes of patients with extensively drug-resistant tuberculosis (XDR-TB) patients and human immunodeficiency virus (HIV) coinfection with and without highly active antiretroviral therapy.Retrospective cohort study. Eligible patients had drug susceptibility testing that met a consensus definition for XDR-TB, and agreed to treatment. Therapy was based on drug susceptibilities, available medications and patient tolerance.Overall, 60 XDR-TB patients initiated therapy with a median number of 5.5 drugs. Of these, 43 (72%) were HIV-positive, and 21 (49%) were on antiretroviral therapy; 29 HIV-infected patients (67%) had available CD4 counts, with a median CD4 count of 200.5 cells/mm(3) (standard deviation 127.4 cells/mm(3)). Of 60 patients, 31 (52%) had adverse events (AEs), and 17/60 patients (28%) had severe AEs. During follow-up, 12/60 (20%) experienced sputum culture conversion, while 25/60 (42%) patients died. None of the following was significantly associated with mortality: HIV status, previous MDR diagnosis or severe AEs.In this study, it was possible to treat HIV-XDR-TB coinfected patients and prolong survival in a resource-limited setting. We highlight the challenges in treatment, including high frequencies of AEs and death. Expanded identification of cases, prompt referral for treatment, and attention to management of comorbidities may facilitate successful treatment of XDR-TB in HIV-infected patients." @default.
• W1683142258 created "2016-06-24" @default.
• W1683142258 creator A5005161503 @default.
• W1683142258 creator A5048577998 @default.
• W1683142258 creator A5049354356 @default.
• W1683142258 creator A5077923202 @default.
• W1683142258 creator A5084570185 @default.
• W1683142258 date "2009-07-01" @default.
• W1683142258 modified "2023-10-16" @default.
• W1683142258 title "Improved early results for patients with extensively drug-resistant tuberculosis and HIV in South Africa." @default.
• W1683142258 cites W1040499591 @default.
• W1683142258 cites W1963988708 @default.
• W1683142258 cites W1974359669 @default.
• W1683142258 cites W1991591189 @default.
• W1683142258 cites W2022648205 @default.
• W1683142258 cites W2036845418 @default.
• W1683142258 cites W2037513501 @default.
• W1683142258 cites W2042114108 @default.
• W1683142258 cites W2072712241 @default.
• W1683142258 cites W2073125281 @default.
• W1683142258 cites W2103230556 @default.
• W1683142258 cites W2104381135 @default.
• W1683142258 cites W2104654339 @default.
• W1683142258 cites W2106577520 @default.
• W1683142258 cites W2114428335 @default.
• W1683142258 cites W2116175177 @default.
• W1683142258 cites W2122450139 @default.
• W1683142258 cites W2136694704 @default.
• W1683142258 cites W2143195179 @default.
• W1683142258 cites W2146921865 @default.
• W1683142258 cites W2149486649 @default.
• W1683142258 cites W2154962788 @default.
• W1683142258 cites W2161515661 @default.
• W1683142258 cites W2170377094 @default.
• W1683142258 cites W2171567087 @default.
• W1683142258 cites W55019144 @default.
• W1683142258 cites W2419344891 @default.
• W1683142258 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2855970" @default.
• W1683142258 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19555535" @default.
• W1683142258 hasPublicationYear "2009" @default.
• W1683142258 type Work @default.
• W1683142258 sameAs 1683142258 @default.
• W1683142258 citedByCount "24" @default.
• W1683142258 countsByYear W16831422582012 @default.
• W1683142258 countsByYear W16831422582013 @default.
• W1683142258 countsByYear W16831422582014 @default.
• W1683142258 countsByYear W16831422582015 @default.
• W1683142258 countsByYear W16831422582017 @default.
• W1683142258 countsByYear W16831422582018 @default.
• W1683142258 countsByYear W16831422582022 @default.
• W1683142258 crossrefType "journal-article" @default.
• W1683142258 hasAuthorship W1683142258A5005161503 @default.
• W1683142258 hasAuthorship W1683142258A5048577998 @default.
• W1683142258 hasAuthorship W1683142258A5049354356 @default.
• W1683142258 hasAuthorship W1683142258A5077923202 @default.
• W1683142258 hasAuthorship W1683142258A5084570185 @default.
• W1683142258 hasConcept C126322002 @default.
• W1683142258 hasConcept C142462285 @default.
• W1683142258 hasConcept C142724271 @default.
• W1683142258 hasConcept C167135981 @default.
• W1683142258 hasConcept C197934379 @default.
• W1683142258 hasConcept C203014093 @default.
• W1683142258 hasConcept C2776135927 @default.
• W1683142258 hasConcept C2776301714 @default.
• W1683142258 hasConcept C2777107064 @default.
• W1683142258 hasConcept C2777813720 @default.
• W1683142258 hasConcept C2777975735 @default.
• W1683142258 hasConcept C2781069245 @default.
• W1683142258 hasConcept C2781432083 @default.
• W1683142258 hasConcept C2993143319 @default.
• W1683142258 hasConcept C3013748606 @default.
• W1683142258 hasConcept C512399662 @default.
• W1683142258 hasConcept C71924100 @default.
• W1683142258 hasConcept C72563966 @default.
• W1683142258 hasConceptScore W1683142258C126322002 @default.
• W1683142258 hasConceptScore W1683142258C142462285 @default.
• W1683142258 hasConceptScore W1683142258C142724271 @default.
• W1683142258 hasConceptScore W1683142258C167135981 @default.
• W1683142258 hasConceptScore W1683142258C197934379 @default.
• W1683142258 hasConceptScore W1683142258C203014093 @default.
• W1683142258 hasConceptScore W1683142258C2776135927 @default.
• W1683142258 hasConceptScore W1683142258C2776301714 @default.
• W1683142258 hasConceptScore W1683142258C2777107064 @default.
• W1683142258 hasConceptScore W1683142258C2777813720 @default.
• W1683142258 hasConceptScore W1683142258C2777975735 @default.
• W1683142258 hasConceptScore W1683142258C2781069245 @default.
• W1683142258 hasConceptScore W1683142258C2781432083 @default.
• W1683142258 hasConceptScore W1683142258C2993143319 @default.
• W1683142258 hasConceptScore W1683142258C3013748606 @default.
• W1683142258 hasConceptScore W1683142258C512399662 @default.
• W1683142258 hasConceptScore W1683142258C71924100 @default.
• W1683142258 hasConceptScore W1683142258C72563966 @default.
• W1683142258 hasLocation W16831422581 @default.
• W1683142258 hasOpenAccess W1683142258 @default.
• W1683142258 hasPrimaryLocation W16831422581 @default.
• W1683142258 hasRelatedWork W1973053638 @default.
• W1683142258 hasRelatedWork W1981137592 @default.
• W1683142258 hasRelatedWork W2049723770 @default.
• W1683142258 hasRelatedWork W2085282522 @default.
• W1683142258 hasRelatedWork W2090122937 @default.

• next