FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1684685502> ?p ?o ?g. }

• W1684685502 endingPage "152" @default.
• W1684685502 startingPage "142" @default.
• W1684685502 abstract "We characterized the underlying mechanisms by which glutathione (GSH)-enhanced natural killer (NK) cells inhibit the growth of Mycobacterium tuberculosis (M. tb) inside human monocytes. We observed that in healthy individuals, treatment of NK cells with N-acetyl cysteine (NAC), a GSH prodrug in conjunction with cytokines such as interleukin (IL)-2 + IL-12, resulted in enhanced expression of NK cytotoxic ligands (FasL and CD40L) with concomitant stasis in the intracellular growth of M. tb. Neutralization of FasL and CD40L in IL-2 + IL-12 + NAC-treated NK cells resulted in abrogation in the growth inhibition of M. tb inside monocytes. Importantly, we observed that the levels of GSH are decreased significantly in NK cells derived from individuals with HIV infection compared to healthy subjects, and this decrease correlated with a several-fold increase in the growth of M. tb inside monocytes. This study describes a novel innate defence mechanism adopted by NK cells to control M. tb infection." @default.
• W1684685502 created "2016-06-24" @default.
• W1684685502 creator A5003131324 @default.
• W1684685502 creator A5028929113 @default.
• W1684685502 creator A5031377702 @default.
• W1684685502 creator A5037389075 @default.
• W1684685502 creator A5048077366 @default.
• W1684685502 creator A5052466700 @default.
• W1684685502 creator A5052816794 @default.
• W1684685502 creator A5085475681 @default.
• W1684685502 creator A5087634879 @default.
• W1684685502 date "2012-03-02" @default.
• W1684685502 modified "2023-10-18" @default.
• W1684685502 title "Control of<i>Mycobacterium tuberculosis</i>growth by activated natural killer cells" @default.
• W1684685502 cites W1607065242 @default.
• W1684685502 cites W1655756854 @default.
• W1684685502 cites W1831891388 @default.
• W1684685502 cites W1892147813 @default.
• W1684685502 cites W1932520996 @default.
• W1684685502 cites W1989953524 @default.
• W1684685502 cites W2038636697 @default.
• W1684685502 cites W2049634987 @default.
• W1684685502 cites W2052098002 @default.
• W1684685502 cites W2055603968 @default.
• W1684685502 cites W2058522060 @default.
• W1684685502 cites W2068923616 @default.
• W1684685502 cites W2076415129 @default.
• W1684685502 cites W2090549085 @default.
• W1684685502 cites W2093955374 @default.
• W1684685502 cites W2111027244 @default.
• W1684685502 cites W2133128339 @default.
• W1684685502 cites W2138358695 @default.
• W1684685502 cites W2138384967 @default.
• W1684685502 cites W2149051564 @default.
• W1684685502 cites W2154518608 @default.
• W1684685502 cites W2165012680 @default.
• W1684685502 doi "https://doi.org/10.1111/j.1365-2249.2011.04552.x" @default.
• W1684685502 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3390505" @default.
• W1684685502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22385249" @default.
• W1684685502 hasPublicationYear "2012" @default.
• W1684685502 type Work @default.
• W1684685502 sameAs 1684685502 @default.
• W1684685502 citedByCount "65" @default.
• W1684685502 countsByYear W16846855022012 @default.
• W1684685502 countsByYear W16846855022013 @default.
• W1684685502 countsByYear W16846855022014 @default.
• W1684685502 countsByYear W16846855022015 @default.
• W1684685502 countsByYear W16846855022016 @default.
• W1684685502 countsByYear W16846855022017 @default.
• W1684685502 countsByYear W16846855022018 @default.
• W1684685502 countsByYear W16846855022019 @default.
• W1684685502 countsByYear W16846855022020 @default.
• W1684685502 countsByYear W16846855022021 @default.
• W1684685502 countsByYear W16846855022022 @default.
• W1684685502 countsByYear W16846855022023 @default.
• W1684685502 crossrefType "journal-article" @default.
• W1684685502 hasAuthorship W1684685502A5003131324 @default.
• W1684685502 hasAuthorship W1684685502A5028929113 @default.
• W1684685502 hasAuthorship W1684685502A5031377702 @default.
• W1684685502 hasAuthorship W1684685502A5037389075 @default.
• W1684685502 hasAuthorship W1684685502A5048077366 @default.
• W1684685502 hasAuthorship W1684685502A5052466700 @default.
• W1684685502 hasAuthorship W1684685502A5052816794 @default.
• W1684685502 hasAuthorship W1684685502A5085475681 @default.
• W1684685502 hasAuthorship W1684685502A5087634879 @default.
• W1684685502 hasBestOaLocation W16846855021 @default.
• W1684685502 hasConcept C129374314 @default.
• W1684685502 hasConcept C142724271 @default.
• W1684685502 hasConcept C149532602 @default.
• W1684685502 hasConcept C154317977 @default.
• W1684685502 hasConcept C167672396 @default.
• W1684685502 hasConcept C181199279 @default.
• W1684685502 hasConcept C202751555 @default.
• W1684685502 hasConcept C203014093 @default.
• W1684685502 hasConcept C2777975735 @default.
• W1684685502 hasConcept C2778102761 @default.
• W1684685502 hasConcept C2780841837 @default.
• W1684685502 hasConcept C2781069245 @default.
• W1684685502 hasConcept C538909803 @default.
• W1684685502 hasConcept C55493867 @default.
• W1684685502 hasConcept C71924100 @default.
• W1684685502 hasConcept C86803240 @default.
• W1684685502 hasConcept C8891405 @default.
• W1684685502 hasConceptScore W1684685502C129374314 @default.
• W1684685502 hasConceptScore W1684685502C142724271 @default.
• W1684685502 hasConceptScore W1684685502C149532602 @default.
• W1684685502 hasConceptScore W1684685502C154317977 @default.
• W1684685502 hasConceptScore W1684685502C167672396 @default.
• W1684685502 hasConceptScore W1684685502C181199279 @default.
• W1684685502 hasConceptScore W1684685502C202751555 @default.
• W1684685502 hasConceptScore W1684685502C203014093 @default.
• W1684685502 hasConceptScore W1684685502C2777975735 @default.
• W1684685502 hasConceptScore W1684685502C2778102761 @default.
• W1684685502 hasConceptScore W1684685502C2780841837 @default.
• W1684685502 hasConceptScore W1684685502C2781069245 @default.
• W1684685502 hasConceptScore W1684685502C538909803 @default.
• W1684685502 hasConceptScore W1684685502C55493867 @default.
• W1684685502 hasConceptScore W1684685502C71924100 @default.

• next