FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1687102912> ?p ?o ?g. }

• W1687102912 endingPage "562" @default.
• W1687102912 startingPage "556" @default.
• W1687102912 abstract "Jumping translocations (JT) are uncommon cytogenetic abnormalities involving nonreciprocal translocations of a single donor chromosome onto 2 or more chromosomes. The clinical characteristics and prognosis of JTs in patients with myeloid malignancies are not well described.We searched our cytogenetic database from 2003 to 2014 to identify cases of myeloid malignancies associated with a JT. These cases were cross-referenced with our clinical databases to determine patient characteristics, response to treatment and overall survival.We identified 10 patients with myeloid malignancies and a JT: 4 cases of acute myeloid leukemia with myelodysplastic syndrome-related changes, 4 cases of myelodysplastic syndrome, and 2 cases of postpolycythemia myelofibrosis. The donor segment was derived from chromosome 1 in every case. The acquisition of a JT was a late occurrence, with a median time to JT development of 24.9 months (range, 0-248 months) from diagnosis. The overall response to treatment was poor, with no patients experiencing a response to conventional chemotherapy or hypomethylating agents. The median overall survival for the group was 9 months (95% confidence interval, 2.5-15.5) after identification of a JT.The acquisition of a JT in patients with myeloid malignancies appears to be a late event and is associated with myelodysplasia. In our series, this was associated with a poor prognosis with a poor response to treatment, disease transformation to acute myeloid leukemia, and short overall survival." @default.
• W1687102912 created "2016-06-24" @default.
• W1687102912 creator A5000750846 @default.
• W1687102912 creator A5010786159 @default.
• W1687102912 creator A5013684062 @default.
• W1687102912 creator A5015140142 @default.
• W1687102912 creator A5049385583 @default.
• W1687102912 creator A5055404021 @default.
• W1687102912 creator A5061026876 @default.
• W1687102912 creator A5085521139 @default.
• W1687102912 creator A5090435894 @default.
• W1687102912 date "2015-09-01" @default.
• W1687102912 modified "2023-10-15" @default.
• W1687102912 title "Jumping Translocations in Myeloid Malignancies Associated With Treatment Resistance and Poor Survival" @default.
• W1687102912 cites W1494138467 @default.
• W1687102912 cites W1534965621 @default.
• W1687102912 cites W1981229272 @default.
• W1687102912 cites W1985046044 @default.
• W1687102912 cites W1990694402 @default.
• W1687102912 cites W1991631671 @default.
• W1687102912 cites W2010298229 @default.
• W1687102912 cites W2010567185 @default.
• W1687102912 cites W2026320696 @default.
• W1687102912 cites W2026995909 @default.
• W1687102912 cites W2053484677 @default.
• W1687102912 cites W2068493370 @default.
• W1687102912 cites W207629 @default.
• W1687102912 cites W2092065403 @default.
• W1687102912 cites W2117383442 @default.
• W1687102912 cites W2129430680 @default.
• W1687102912 cites W2129510594 @default.
• W1687102912 cites W2156347846 @default.
• W1687102912 cites W2159507916 @default.
• W1687102912 cites W2313800436 @default.
• W1687102912 cites W2326726820 @default.
• W1687102912 cites W4245775480 @default.
• W1687102912 cites W4376595466 @default.
• W1687102912 doi "https://doi.org/10.1016/j.clml.2015.05.005" @default.
• W1687102912 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4837956" @default.
• W1687102912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26141213" @default.
• W1687102912 hasPublicationYear "2015" @default.
• W1687102912 type Work @default.
• W1687102912 sameAs 1687102912 @default.
• W1687102912 citedByCount "7" @default.
• W1687102912 countsByYear W16871029122017 @default.
• W1687102912 countsByYear W16871029122019 @default.
• W1687102912 countsByYear W16871029122020 @default.
• W1687102912 countsByYear W16871029122022 @default.
• W1687102912 crossrefType "journal-article" @default.
• W1687102912 hasAuthorship W1687102912A5000750846 @default.
• W1687102912 hasAuthorship W1687102912A5010786159 @default.
• W1687102912 hasAuthorship W1687102912A5013684062 @default.
• W1687102912 hasAuthorship W1687102912A5015140142 @default.
• W1687102912 hasAuthorship W1687102912A5049385583 @default.
• W1687102912 hasAuthorship W1687102912A5055404021 @default.
• W1687102912 hasAuthorship W1687102912A5061026876 @default.
• W1687102912 hasAuthorship W1687102912A5085521139 @default.
• W1687102912 hasAuthorship W1687102912A5090435894 @default.
• W1687102912 hasBestOaLocation W16871029122 @default.
• W1687102912 hasConcept C104317684 @default.
• W1687102912 hasConcept C126322002 @default.
• W1687102912 hasConcept C138626823 @default.
• W1687102912 hasConcept C143998085 @default.
• W1687102912 hasConcept C2778729363 @default.
• W1687102912 hasConcept C2779282312 @default.
• W1687102912 hasConcept C2780007613 @default.
• W1687102912 hasConcept C2780076729 @default.
• W1687102912 hasConcept C2780817109 @default.
• W1687102912 hasConcept C55493867 @default.
• W1687102912 hasConcept C71924100 @default.
• W1687102912 hasConcept C86803240 @default.
• W1687102912 hasConceptScore W1687102912C104317684 @default.
• W1687102912 hasConceptScore W1687102912C126322002 @default.
• W1687102912 hasConceptScore W1687102912C138626823 @default.
• W1687102912 hasConceptScore W1687102912C143998085 @default.
• W1687102912 hasConceptScore W1687102912C2778729363 @default.
• W1687102912 hasConceptScore W1687102912C2779282312 @default.
• W1687102912 hasConceptScore W1687102912C2780007613 @default.
• W1687102912 hasConceptScore W1687102912C2780076729 @default.
• W1687102912 hasConceptScore W1687102912C2780817109 @default.
• W1687102912 hasConceptScore W1687102912C55493867 @default.
• W1687102912 hasConceptScore W1687102912C71924100 @default.
• W1687102912 hasConceptScore W1687102912C86803240 @default.
• W1687102912 hasIssue "9" @default.
• W1687102912 hasLocation W16871029121 @default.
• W1687102912 hasLocation W16871029122 @default.
• W1687102912 hasLocation W16871029123 @default.
• W1687102912 hasLocation W16871029124 @default.
• W1687102912 hasOpenAccess W1687102912 @default.
• W1687102912 hasPrimaryLocation W16871029121 @default.
• W1687102912 hasRelatedWork W2020830345 @default.
• W1687102912 hasRelatedWork W2021175744 @default.
• W1687102912 hasRelatedWork W2026865731 @default.
• W1687102912 hasRelatedWork W2031303146 @default.
• W1687102912 hasRelatedWork W2033346957 @default.
• W1687102912 hasRelatedWork W2074561855 @default.
• W1687102912 hasRelatedWork W2158556487 @default.
• W1687102912 hasRelatedWork W2167931562 @default.

• next