Matches in SemOpenAlex for { <https://semopenalex.org/work/W1690676535> ?p ?o ?g. }
- W1690676535 abstract "Several hundred thousand primordial follicles are present in the mammalian ovary, however, only 1% develop to the preovulatory stage and finally ovulate. The remainder will be eliminated via a degenerative process called ‘atresia’. The endocrinological regulatory mechanisms involved in follicular development and atresia have largely been characterized but the precise temporal and molecular mechanisms involved in the regulation of these events remain unknown. Many recent studies suggest that apoptosis in ovarian granulosa cells plays a crucial role in follicular atresia. Notably, death ligand-receptor interaction and subsequent intracellular signaling have been demonstrated to be the key mechanisms regulating granulosa cell apoptosis. In this review we provide an overview of granulosa cell apoptosis regulated by death ligand-receptor signaling. The roles of death ligands and receptors [Fas ligand (FasL)]-Fas, tumor necrosis factor α (TNFα)-TNF receptor and TNFα-related apoptosis-inducing ligand (TRAIL)-TRAIL receptor (TRAILR)] and intracellular death-signal mediating molecules (Fas-associated death domain protein), TNF receptor 1-associated death domain protein, caspases, apoptotic protease-activating factor 1, TNFR-associated factor 2 and cellular FLICE-like inhibitory protein in granulosa cells are discussed." @default.
- W1690676535 created "2016-06-24" @default.
- W1690676535 creator A5013671018 @default.
- W1690676535 creator A5025075688 @default.
- W1690676535 creator A5029114920 @default.
- W1690676535 creator A5046396847 @default.
- W1690676535 creator A5050731848 @default.
- W1690676535 creator A5053726996 @default.
- W1690676535 creator A5088133012 @default.
- W1690676535 date "2007-10-26" @default.
- W1690676535 modified "2023-10-18" @default.
- W1690676535 title "Regulation of granulosa cell apoptosis by death ligand-receptor signaling" @default.
- W1690676535 cites W1534163224 @default.
- W1690676535 cites W1964262197 @default.
- W1690676535 cites W1967999114 @default.
- W1690676535 cites W1968529653 @default.
- W1690676535 cites W1968747163 @default.
- W1690676535 cites W1970315882 @default.
- W1690676535 cites W1973109581 @default.
- W1690676535 cites W1975315198 @default.
- W1690676535 cites W1979664116 @default.
- W1690676535 cites W1980919524 @default.
- W1690676535 cites W1984709119 @default.
- W1690676535 cites W1985138230 @default.
- W1690676535 cites W1986308149 @default.
- W1690676535 cites W1990414415 @default.
- W1690676535 cites W2002503549 @default.
- W1690676535 cites W2012008394 @default.
- W1690676535 cites W2017380974 @default.
- W1690676535 cites W2017728303 @default.
- W1690676535 cites W2017985723 @default.
- W1690676535 cites W2020680466 @default.
- W1690676535 cites W2021833524 @default.
- W1690676535 cites W2022247016 @default.
- W1690676535 cites W2025128734 @default.
- W1690676535 cites W2030892254 @default.
- W1690676535 cites W2031004067 @default.
- W1690676535 cites W2035091743 @default.
- W1690676535 cites W2036528355 @default.
- W1690676535 cites W2039909111 @default.
- W1690676535 cites W2044501754 @default.
- W1690676535 cites W2044757103 @default.
- W1690676535 cites W2045390070 @default.
- W1690676535 cites W2045923190 @default.
- W1690676535 cites W2048427763 @default.
- W1690676535 cites W2052930354 @default.
- W1690676535 cites W2055759603 @default.
- W1690676535 cites W2056217426 @default.
- W1690676535 cites W2058773384 @default.
- W1690676535 cites W2062008354 @default.
- W1690676535 cites W2064982197 @default.
- W1690676535 cites W2069785765 @default.
- W1690676535 cites W2071981344 @default.
- W1690676535 cites W2074122408 @default.
- W1690676535 cites W2077615630 @default.
- W1690676535 cites W2081141076 @default.
- W1690676535 cites W2083568300 @default.
- W1690676535 cites W2083957336 @default.
- W1690676535 cites W2087079563 @default.
- W1690676535 cites W2088291142 @default.
- W1690676535 cites W2089900969 @default.
- W1690676535 cites W2093442889 @default.
- W1690676535 cites W2094334993 @default.
- W1690676535 cites W2099014342 @default.
- W1690676535 cites W2100636699 @default.
- W1690676535 cites W2102325885 @default.
- W1690676535 cites W2106168906 @default.
- W1690676535 cites W2106876536 @default.
- W1690676535 cites W2108992248 @default.
- W1690676535 cites W2110307590 @default.
- W1690676535 cites W2111159854 @default.
- W1690676535 cites W2113310606 @default.
- W1690676535 cites W2114468088 @default.
- W1690676535 cites W2119299816 @default.
- W1690676535 cites W2123373604 @default.
- W1690676535 cites W2127250453 @default.
- W1690676535 cites W2130978990 @default.
- W1690676535 cites W2130988210 @default.
- W1690676535 cites W2132686612 @default.
- W1690676535 cites W2132778480 @default.
- W1690676535 cites W2133726754 @default.
- W1690676535 cites W2135081724 @default.
- W1690676535 cites W2138946240 @default.
- W1690676535 cites W2148321928 @default.
- W1690676535 cites W2150536749 @default.
- W1690676535 cites W2151718422 @default.
- W1690676535 cites W2152403069 @default.
- W1690676535 cites W2152445095 @default.
- W1690676535 cites W2158726961 @default.
- W1690676535 cites W2168967452 @default.
- W1690676535 cites W2181430872 @default.
- W1690676535 cites W2328332463 @default.
- W1690676535 cites W4250256124 @default.
- W1690676535 doi "https://doi.org/10.1111/j.1467-8381.2008.00272.x-i1" @default.
- W1690676535 hasPublicationYear "2007" @default.
- W1690676535 type Work @default.
- W1690676535 sameAs 1690676535 @default.
- W1690676535 citedByCount "15" @default.
- W1690676535 countsByYear W16906765352012 @default.
- W1690676535 countsByYear W16906765352013 @default.