FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1691554648> ?p ?o ?g. }

• W1691554648 endingPage "5853" @default.
• W1691554648 startingPage "5853" @default.
• W1691554648 abstract "Hericium erinaceus has been reported to have a wide range of medicinal properties such as stimulation of neurite outgrowth, promotion of functional recovery of axonotmetic peroneal nerve injury, antioxidant, antihypertensive, and antidiabetic properties. In recent years, the green synthesis of gold nanoparticles (AuNPs) has attracted intense interest due to the potential use in biomedical applications. The aim of this study was to investigate the effects of AuNPs from aqueous extract of H. erinaceus on neurite outgrowth of rat pheochromocytoma (PC-12) cells.The formation of AuNPs was characterized by UV-visible spectrum, energy dispersive X-ray (EDX), field-emission scanning electron microscope (FESEM), transmission electron microscopy (TEM), particle size distribution, and Fourier transform-infrared spectroscopy (FTIR). Furthermore, the neurite extension study of synthesized AuNPs was evaluated by in vitro assay.The AuNPs exhibited maximum absorbance between 510 and 600 nm in UV-visible spectrum. FESEM and TEM images showed the existence of nanoparticles with sizes of 20-40 nm. FTIR measurements were carried out to identify the possible biomolecules responsible for capping and efficient stabilization of the nanoparticles. The purity and the crystalline properties were confirmed by EDX diffraction analysis, which showed strong signals with energy peaks in the range of 2-2.4 keV, indicating the existence of gold atoms. The synthesized AuNPs showed significant neurite extension on PC-12 cells. Nerve growth factor 50 ng/mL was used as a positive control. Treatment with different concentrations (nanograms) of AuNPs resulted in neuronal differentiation and neuronal elongation. AuNPs induced maximum neurite outgrowth of 13% at 600 ng/mL concentration.In this study, the AuNPs synthesis was achieved by a simple, low-cost, and rapid bioreduction approach. AuNPs were shown to have potential neuronal differentiation and stimulated neurite outgrowth. The water-soluble bioconstituents could be responsible for the neuroactivity. This is the first report for the biosynthesis of AuNPs using the hot aqueous extract of H. erinaceus." @default.
• W1691554648 created "2016-06-24" @default.
• W1691554648 creator A5016217111 @default.
• W1691554648 creator A5020656047 @default.
• W1691554648 creator A5026750048 @default.
• W1691554648 creator A5031744197 @default.
• W1691554648 creator A5043325166 @default.
• W1691554648 creator A5046632430 @default.
• W1691554648 creator A5057349325 @default.
• W1691554648 creator A5088331883 @default.
• W1691554648 date "2015-09-01" @default.
• W1691554648 modified "2023-09-23" @default.
• W1691554648 title "Neurite outgrowth stimulatory effects of myco&shy;synthesized AuNPs from Hericium erinaceus (Bull.: Fr.) Pers. on pheochromocytoma (PC-12) cells" @default.
• W1691554648 cites W1535983901 @default.
• W1691554648 cites W1581014867 @default.
• W1691554648 cites W1699606929 @default.
• W1691554648 cites W1984883082 @default.
• W1691554648 cites W1989036685 @default.
• W1691554648 cites W1996357647 @default.
• W1691554648 cites W1997645270 @default.
• W1691554648 cites W1999912232 @default.
• W1691554648 cites W2001644643 @default.
• W1691554648 cites W2002484911 @default.
• W1691554648 cites W2018289835 @default.
• W1691554648 cites W2033831066 @default.
• W1691554648 cites W2039911198 @default.
• W1691554648 cites W2041200728 @default.
• W1691554648 cites W2043026906 @default.
• W1691554648 cites W2061796336 @default.
• W1691554648 cites W2068021889 @default.
• W1691554648 cites W2069457858 @default.
• W1691554648 cites W2073518011 @default.
• W1691554648 cites W2079407969 @default.
• W1691554648 cites W2084948591 @default.
• W1691554648 cites W2099327069 @default.
• W1691554648 cites W2099584751 @default.
• W1691554648 cites W2100837269 @default.
• W1691554648 cites W2128635872 @default.
• W1691554648 cites W2149210955 @default.
• W1691554648 cites W2163931885 @default.
• W1691554648 cites W2165093484 @default.
• W1691554648 cites W2168007569 @default.
• W1691554648 doi "https://doi.org/10.2147/ijn.s88371" @default.
• W1691554648 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4583117" @default.
• W1691554648 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26425086" @default.
• W1691554648 hasPublicationYear "2015" @default.
• W1691554648 type Work @default.
• W1691554648 sameAs 1691554648 @default.
• W1691554648 citedByCount "2" @default.
• W1691554648 countsByYear W16915546482021 @default.
• W1691554648 countsByYear W16915546482022 @default.
• W1691554648 crossrefType "journal-article" @default.
• W1691554648 hasAuthorship W1691554648A5016217111 @default.
• W1691554648 hasAuthorship W1691554648A5020656047 @default.
• W1691554648 hasAuthorship W1691554648A5026750048 @default.
• W1691554648 hasAuthorship W1691554648A5031744197 @default.
• W1691554648 hasAuthorship W1691554648A5043325166 @default.
• W1691554648 hasAuthorship W1691554648A5046632430 @default.
• W1691554648 hasAuthorship W1691554648A5057349325 @default.
• W1691554648 hasAuthorship W1691554648A5088331883 @default.
• W1691554648 hasBestOaLocation W16915546481 @default.
• W1691554648 hasConcept C104819515 @default.
• W1691554648 hasConcept C113246987 @default.
• W1691554648 hasConcept C12554922 @default.
• W1691554648 hasConcept C127413603 @default.
• W1691554648 hasConcept C13965031 @default.
• W1691554648 hasConcept C146088050 @default.
• W1691554648 hasConcept C155672457 @default.
• W1691554648 hasConcept C159985019 @default.
• W1691554648 hasConcept C160892712 @default.
• W1691554648 hasConcept C171250308 @default.
• W1691554648 hasConcept C178790620 @default.
• W1691554648 hasConcept C185592680 @default.
• W1691554648 hasConcept C192562407 @default.
• W1691554648 hasConcept C202751555 @default.
• W1691554648 hasConcept C206139338 @default.
• W1691554648 hasConcept C2777545159 @default.
• W1691554648 hasConcept C42360764 @default.
• W1691554648 hasConcept C46275449 @default.
• W1691554648 hasConcept C55493867 @default.
• W1691554648 hasConcept C86803240 @default.
• W1691554648 hasConceptScore W1691554648C104819515 @default.
• W1691554648 hasConceptScore W1691554648C113246987 @default.
• W1691554648 hasConceptScore W1691554648C12554922 @default.
• W1691554648 hasConceptScore W1691554648C127413603 @default.
• W1691554648 hasConceptScore W1691554648C13965031 @default.
• W1691554648 hasConceptScore W1691554648C146088050 @default.
• W1691554648 hasConceptScore W1691554648C155672457 @default.
• W1691554648 hasConceptScore W1691554648C159985019 @default.
• W1691554648 hasConceptScore W1691554648C160892712 @default.
• W1691554648 hasConceptScore W1691554648C171250308 @default.
• W1691554648 hasConceptScore W1691554648C178790620 @default.
• W1691554648 hasConceptScore W1691554648C185592680 @default.
• W1691554648 hasConceptScore W1691554648C192562407 @default.
• W1691554648 hasConceptScore W1691554648C202751555 @default.
• W1691554648 hasConceptScore W1691554648C206139338 @default.
• W1691554648 hasConceptScore W1691554648C2777545159 @default.
• W1691554648 hasConceptScore W1691554648C42360764 @default.

• next