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- W169159906 abstract "SUMMARY The use of alpha-fetoprotein (AFP) in the diagnosis of liver cell cancer is invaluable; most cases can be accurately diagnosed or justification can be provided to pursue the diagnosis by other means. Whether or not the measurement of AFP is justified as an epidemiological tool is doubtful since there is a normal AFP level (the effects of subclinical hepatitis altering this normal level) and since liver cell cancer is, in general, not responsive to treatment. As a model system to demonstrate the possibilities of an early cancer detection system, the AFP test has exposed some interesting problems. Do all cancers grow to the clinical or sub-clinical stage as rapidly as liver cell cancer in southern Africa appears to do? Is the promotion of tumour growth really so dramatically triggered and is the initial transformation perhaps less significant in the time scale? Further prospective surveys using the quantitation which radioimmunoassay can provide are required, hopefully, to answer some of these questions before we can hope to intervene in the development of the early stages of the evolving cancer to the benefit of the patient." @default.
- W169159906 created "2016-06-24" @default.
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- W169159906 date "1976-01-01" @default.
- W169159906 modified "2023-09-26" @default.
- W169159906 title "ALPHA-FETOPROTEIN AND THE DIAGNOSIS OF LIVER CELL CANCER" @default.
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- W169159906 doi "https://doi.org/10.1016/b978-0-444-41542-4.50008-0" @default.
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