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- W169625388 abstract "There is general agreement that the CD4+ T lymphocyte is responsible for initiating and regulating the immune response to most antigens. The activation of CD4+ T cells requires recognition of antigen-derived peptides associated with MHC class II. In rodents, whereas many cells expressing MHC II can present antigen to activated T cells, there is good evidence that resting Tcells are only activated efficiently by a specialised cell type, the lymphoid-dendritic cell.1 There exist two distinct, and very probably unrelated kinds of dendritic cells (DC) which are involved in immune responses. The follicular DC is present B cell areas of secondary lymphoid tissues, is probably not bone-marrow derived, is long lived, retains immune complexes on its surface for presenting to B cells and will not be considered further here. The other, the lymphoid DC is specialised for the presentation of antigen to T cells, and is probably of particular importance in primary responses." @default.
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- W169625388 date "1995-01-01" @default.
- W169625388 modified "2023-09-26" @default.
- W169625388 title "Dendritic Cells “In Vivo”: Their Role in the Initiation of Intestinal Immune Responses" @default.
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- W169625388 doi "https://doi.org/10.1007/978-1-4615-1941-6_56" @default.
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