Matches in SemOpenAlex for { <https://semopenalex.org/work/W1696286945> ?p ?o ?g. }
- W1696286945 endingPage "110" @default.
- W1696286945 startingPage "110" @default.
- W1696286945 abstract "Objective: To investigate whether polymorphisms in the estrogen receptor alpha (ESR1) and beta (ESR2) genes were a risk factor for open-angle glaucoma (OAG). Methods: Participants 55 years and older from the population-based Rotterdam Study underwent, at baseline and at follow-up, the same ophthalmic examination, including visual field screening and stereo optic disc photography. A diagnosis of OAG was based on an algorithm using optic disc measures and visual field loss. Haplotypes of the ESR1 and ESR2 genes were determined. Results: We diagnosed incident OAG in 87 of 3842 participants (2.3%) at risk after a mean follow-up of 6.5 years. We could not detect any association with ESR1 haplotypes. Haplotype 1 of ESR2 showed a 3.6-fold (95% confidence interval, 1.4-9.2) higher risk of incident OAG in men. In women, no association was found between ESR2 and incident OAG. Conclusion: Polymorphisms in the ESR1 gene are unrelated to OAG, but ESR2 polymorphisms seem to lead to increased risk of OAG in men." @default.
- W1696286945 created "2016-06-24" @default.
- W1696286945 creator A5003042037 @default.
- W1696286945 creator A5003574809 @default.
- W1696286945 creator A5004755706 @default.
- W1696286945 creator A5031530236 @default.
- W1696286945 creator A5039611937 @default.
- W1696286945 creator A5057740085 @default.
- W1696286945 creator A5079798885 @default.
- W1696286945 date "2008-01-01" @default.
- W1696286945 modified "2023-10-08" @default.
- W1696286945 title "Estrogen Receptors Alpha and Beta and the Risk of Open-angle Glaucoma" @default.
- W1696286945 cites W1488271316 @default.
- W1696286945 cites W1780762990 @default.
- W1696286945 cites W1910188440 @default.
- W1696286945 cites W1965952143 @default.
- W1696286945 cites W1966037055 @default.
- W1696286945 cites W1974956023 @default.
- W1696286945 cites W1990245848 @default.
- W1696286945 cites W1991455388 @default.
- W1696286945 cites W1998122804 @default.
- W1696286945 cites W2003998919 @default.
- W1696286945 cites W2006417886 @default.
- W1696286945 cites W2024475596 @default.
- W1696286945 cites W2029870946 @default.
- W1696286945 cites W2039441819 @default.
- W1696286945 cites W2042335805 @default.
- W1696286945 cites W2048728589 @default.
- W1696286945 cites W2060819029 @default.
- W1696286945 cites W2077243943 @default.
- W1696286945 cites W2079481914 @default.
- W1696286945 cites W2087671892 @default.
- W1696286945 cites W2089676562 @default.
- W1696286945 cites W2098317776 @default.
- W1696286945 cites W2106364918 @default.
- W1696286945 cites W2108681892 @default.
- W1696286945 cites W2110755408 @default.
- W1696286945 cites W2114725993 @default.
- W1696286945 cites W2119857277 @default.
- W1696286945 cites W2123977931 @default.
- W1696286945 cites W2136405724 @default.
- W1696286945 cites W2137432207 @default.
- W1696286945 cites W2144645229 @default.
- W1696286945 cites W2161311256 @default.
- W1696286945 cites W2163385200 @default.
- W1696286945 cites W2166101050 @default.
- W1696286945 cites W2168691284 @default.
- W1696286945 cites W2401910999 @default.
- W1696286945 cites W2408121173 @default.
- W1696286945 cites W98267065 @default.
- W1696286945 doi "https://doi.org/10.1001/archopht.126.1.110" @default.
- W1696286945 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18195227" @default.
- W1696286945 hasPublicationYear "2008" @default.
- W1696286945 type Work @default.
- W1696286945 sameAs 1696286945 @default.
- W1696286945 citedByCount "23" @default.
- W1696286945 countsByYear W16962869452012 @default.
- W1696286945 countsByYear W16962869452013 @default.
- W1696286945 countsByYear W16962869452014 @default.
- W1696286945 countsByYear W16962869452015 @default.
- W1696286945 countsByYear W16962869452016 @default.
- W1696286945 countsByYear W16962869452018 @default.
- W1696286945 countsByYear W16962869452019 @default.
- W1696286945 countsByYear W16962869452020 @default.
- W1696286945 countsByYear W16962869452021 @default.
- W1696286945 countsByYear W16962869452022 @default.
- W1696286945 crossrefType "journal-article" @default.
- W1696286945 hasAuthorship W1696286945A5003042037 @default.
- W1696286945 hasAuthorship W1696286945A5003574809 @default.
- W1696286945 hasAuthorship W1696286945A5004755706 @default.
- W1696286945 hasAuthorship W1696286945A5031530236 @default.
- W1696286945 hasAuthorship W1696286945A5039611937 @default.
- W1696286945 hasAuthorship W1696286945A5057740085 @default.
- W1696286945 hasAuthorship W1696286945A5079798885 @default.
- W1696286945 hasConcept C118487528 @default.
- W1696286945 hasConcept C121608353 @default.
- W1696286945 hasConcept C126322002 @default.
- W1696286945 hasConcept C141071460 @default.
- W1696286945 hasConcept C199360897 @default.
- W1696286945 hasConcept C2775944032 @default.
- W1696286945 hasConcept C2776174256 @default.
- W1696286945 hasConcept C2777164284 @default.
- W1696286945 hasConcept C2778527774 @default.
- W1696286945 hasConcept C2991803831 @default.
- W1696286945 hasConcept C41008148 @default.
- W1696286945 hasConcept C49453240 @default.
- W1696286945 hasConcept C530470458 @default.
- W1696286945 hasConcept C64943373 @default.
- W1696286945 hasConcept C71924100 @default.
- W1696286945 hasConcept C84606932 @default.
- W1696286945 hasConcept C96307122 @default.
- W1696286945 hasConceptScore W1696286945C118487528 @default.
- W1696286945 hasConceptScore W1696286945C121608353 @default.
- W1696286945 hasConceptScore W1696286945C126322002 @default.
- W1696286945 hasConceptScore W1696286945C141071460 @default.
- W1696286945 hasConceptScore W1696286945C199360897 @default.
- W1696286945 hasConceptScore W1696286945C2775944032 @default.
- W1696286945 hasConceptScore W1696286945C2776174256 @default.