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- W169804972 abstract "Abstract Cellular therapy is the use of viable cells and tissues for the treatment of disease. Cell and tissue donors can be syngeneic, allogeneic, or autologous. Current good tissue and manufacturing practices (cGTP and cGMP, respectively) must be followed to prevent the introduction, transmission, and spread of communicable diseases. Donor qualification, controlled environments, use of sterile supplies and reagents, and assays to ensure the purity and potency of products are required. When selecting a cell type for the development of a cellular therapy, the goals and purpose of the therapy must be considered. The starting cells should be readily available and in sufficient quantities to provide the desired effects. Either stem cells or adult tissue-specific differentiated cells can be used. Stem cells are undifferentiated cells capable of unlimited self-renewal; under appropriate conditions, they differentiate into specific cell type(s). Stem cells are most useful for repair or repopulation of damaged tissues and can be derived from embryonic or adult tissues. Adult tissue-specific differentiated cells may be used when the function of a specific differentiated cell type is desired." @default.
- W169804972 created "2016-06-24" @default.
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- W169804972 date "2013-01-01" @default.
- W169804972 modified "2023-09-24" @default.
- W169804972 title "Overview of Cellular Therapy" @default.
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- W169804972 doi "https://doi.org/10.1016/b978-0-12-397164-7.00081-1" @default.
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