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- W169849809 abstract "This article discusses in vivo NMR and MRI applications of hyperpolarized noble gases. Relevant properties of the most commonly used isotopes 3He and 129Xe are described. An overview of the optical pumping process used to achieve hyperpolarization is given. Issues concerning the implementation of noble gas MRI are discussed, covering both hardware and pulse sequence considerations. The basic gradient echo pulse sequences for MRI of hyperpolarized species are introduced, explaining their bearing on image appearance. Commonly used MRI protocols used for lung diagnostics, such as ventilation imaging, diffusion sensitized imaging, and mapping of intrapulmonary pO2, are explained. Finally, investigation of gas exchange between blood and pulmonary gas spaces by 129Xe exchange methods based on NMR and MRI experiments is described. Sources of information about the use of hyperpolarized gases outside of a clinical context are given in the Further Reading section." @default.
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- W169849809 date "2010-01-01" @default.
- W169849809 modified "2023-10-14" @default.
- W169849809 title "Hyperpolarized Gases in NMR, Methods and Applications" @default.
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- W169849809 doi "https://doi.org/10.1016/b978-0-12-374413-5.00033-6" @default.
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