Matches in SemOpenAlex for { <https://semopenalex.org/work/W1699897968> ?p ?o ?g. }
- W1699897968 endingPage "295" @default.
- W1699897968 startingPage "283" @default.
- W1699897968 abstract "Curcumin is a promising compound that can be used as a theranostic agent to aid research in Alzheimer's disease. Beyond its ability to bind to amyloid plaques, the compound can also cross the blood-brain barrier. Presently, curcumin can be applied only to animal models, as the formulation needed for iv injection renders it unfit for human use. Here, we describe a novel technique to aerosolize a curcumin derivative, FMeC1, and facilitate its safe delivery to the brain. Aside from the translational applicability of this approach, a study in the 5XFAD mouse model suggested that inhalation exposure to an aerosolized FMeC1 modestly improved the distribution of the compound in the brain. Additionally, immunohistochemistry data confirms that following aerosol delivery, FMeC1 binds amyloid plaques expressed in the hippocampal areas and cortex." @default.
- W1699897968 created "2016-06-24" @default.
- W1699897968 creator A5004009433 @default.
- W1699897968 creator A5016773409 @default.
- W1699897968 creator A5040979247 @default.
- W1699897968 creator A5041671833 @default.
- W1699897968 creator A5051041843 @default.
- W1699897968 creator A5067870050 @default.
- W1699897968 creator A5072903603 @default.
- W1699897968 creator A5073448365 @default.
- W1699897968 creator A5073489641 @default.
- W1699897968 creator A5075960927 @default.
- W1699897968 creator A5084194098 @default.
- W1699897968 creator A5090553551 @default.
- W1699897968 date "2015-01-06" @default.
- W1699897968 modified "2023-09-28" @default.
- W1699897968 title "Inhalable Curcumin: Offering the Potential for Translation to Imaging and Treatment of Alzheimer's Disease" @default.
- W1699897968 cites W1486653930 @default.
- W1699897968 cites W1578872259 @default.
- W1699897968 cites W1798792414 @default.
- W1699897968 cites W1828339576 @default.
- W1699897968 cites W1964407607 @default.
- W1699897968 cites W1972179974 @default.
- W1699897968 cites W1973058491 @default.
- W1699897968 cites W1976194786 @default.
- W1699897968 cites W1988545224 @default.
- W1699897968 cites W1999312756 @default.
- W1699897968 cites W2002311445 @default.
- W1699897968 cites W2005543592 @default.
- W1699897968 cites W2022014262 @default.
- W1699897968 cites W2028267884 @default.
- W1699897968 cites W2033356866 @default.
- W1699897968 cites W2034037638 @default.
- W1699897968 cites W2039680628 @default.
- W1699897968 cites W2040330716 @default.
- W1699897968 cites W2041764058 @default.
- W1699897968 cites W2052410449 @default.
- W1699897968 cites W2058012429 @default.
- W1699897968 cites W2067574216 @default.
- W1699897968 cites W2069956399 @default.
- W1699897968 cites W2070801001 @default.
- W1699897968 cites W2079682800 @default.
- W1699897968 cites W2091628499 @default.
- W1699897968 cites W2095019664 @default.
- W1699897968 cites W2100604254 @default.
- W1699897968 cites W2105979117 @default.
- W1699897968 cites W2115123250 @default.
- W1699897968 cites W2117116660 @default.
- W1699897968 cites W2124733101 @default.
- W1699897968 cites W2150322679 @default.
- W1699897968 cites W2152148584 @default.
- W1699897968 cites W2154749390 @default.
- W1699897968 cites W2159879659 @default.
- W1699897968 cites W2167204367 @default.
- W1699897968 cites W2168038826 @default.
- W1699897968 cites W2170644095 @default.
- W1699897968 cites W2189011617 @default.
- W1699897968 cites W2238003553 @default.
- W1699897968 doi "https://doi.org/10.3233/jad-140798" @default.
- W1699897968 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4297252" @default.
- W1699897968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25227316" @default.
- W1699897968 hasPublicationYear "2015" @default.
- W1699897968 type Work @default.
- W1699897968 sameAs 1699897968 @default.
- W1699897968 citedByCount "36" @default.
- W1699897968 countsByYear W16998979682015 @default.
- W1699897968 countsByYear W16998979682016 @default.
- W1699897968 countsByYear W16998979682017 @default.
- W1699897968 countsByYear W16998979682018 @default.
- W1699897968 countsByYear W16998979682019 @default.
- W1699897968 countsByYear W16998979682020 @default.
- W1699897968 countsByYear W16998979682021 @default.
- W1699897968 countsByYear W16998979682022 @default.
- W1699897968 countsByYear W16998979682023 @default.
- W1699897968 crossrefType "journal-article" @default.
- W1699897968 hasAuthorship W1699897968A5004009433 @default.
- W1699897968 hasAuthorship W1699897968A5016773409 @default.
- W1699897968 hasAuthorship W1699897968A5040979247 @default.
- W1699897968 hasAuthorship W1699897968A5041671833 @default.
- W1699897968 hasAuthorship W1699897968A5051041843 @default.
- W1699897968 hasAuthorship W1699897968A5067870050 @default.
- W1699897968 hasAuthorship W1699897968A5072903603 @default.
- W1699897968 hasAuthorship W1699897968A5073448365 @default.
- W1699897968 hasAuthorship W1699897968A5073489641 @default.
- W1699897968 hasAuthorship W1699897968A5075960927 @default.
- W1699897968 hasAuthorship W1699897968A5084194098 @default.
- W1699897968 hasAuthorship W1699897968A5090553551 @default.
- W1699897968 hasBestOaLocation W16998979682 @default.
- W1699897968 hasConcept C104317684 @default.
- W1699897968 hasConcept C105580179 @default.
- W1699897968 hasConcept C142724271 @default.
- W1699897968 hasConcept C148762608 @default.
- W1699897968 hasConcept C149364088 @default.
- W1699897968 hasConcept C15744967 @default.
- W1699897968 hasConcept C169760540 @default.
- W1699897968 hasConcept C185592680 @default.
- W1699897968 hasConcept C2776954882 @default.
- W1699897968 hasConcept C2777633098 @default.