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- W170031768 abstract "Distributed through the core of the brainstem and forebrain, neuronal populations, which utilize particular neurotransmitters and project in a widespread or diffuse manner through ascending relays to the cortex and/or descending relays to the spinal cord, generate sleep–wake states. Ascending systems stimulate cortical activation and include glutamatergic neurons of the reticular formation (RF) and nonspecific thalamo-cortical projection system and cholinergic neurons of the pontomesencephalic tegmentum and basal forebrain (BF). Overlapping diffuse or descending systems also stimulate behavioral arousal with muscle tone and include glutamatergic, noradrenergic, histaminergic, and orexinergic neurons. Neurons of the activating and arousal systems are inhibited during slow-wave sleep (SWS) and/or paradoxical sleep (PS) largely by GABAergic neurons." @default.
- W170031768 created "2016-06-24" @default.
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- W170031768 date "2013-01-01" @default.
- W170031768 modified "2023-09-24" @default.
- W170031768 title "Chemical Neuroanatomy of Sleep–Wake Systems" @default.
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- W170031768 doi "https://doi.org/10.1016/b978-0-12-378610-4.00085-1" @default.
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