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- W1701595965 abstract "Abstract Aims To assess whether early measures of fasting blood glucose predict later glycaemic response with once‐weekly dulaglutide in patients with Type 2 diabetes mellitus. Methods Post hoc analyses were conducted separately for two phase 3 studies ( AWARD –5 and AWARD –1) in patients assigned to once‐weekly dulaglutide. Week 2 fasting blood glucose was used as a predictor variable, and glycaemic treatment response was defined by HbA 1c response based on a composite efficacy endpoint. The association between fasting blood glucose and the glycaemic response was analysed using chi‐square tests. Results There was a strong association between fasting blood glucose < 7.9 mmol/l at week 2 and achieving the HbA 1c composite efficacy endpoint at week 26 ( P < 0.01). Higher fasting blood glucose at week 2, however, did not predict absence of glycaemic response and requires further assessment. Conclusions Fasting blood glucose measured at 2 weeks may be an early and useful predictor of glycaemic response to once‐weekly dulaglutide treatment." @default.
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- W1701595965 date "2015-07-21" @default.
- W1701595965 modified "2023-09-27" @default.
- W1701595965 title "Early fasting glucose measurements can predict later glycaemic response to once weekly dulaglutide" @default.
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- W1701595965 doi "https://doi.org/10.1111/dme.12833" @default.
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