Matches in SemOpenAlex for { <https://semopenalex.org/work/W1703346276> ?p ?o ?g. }
- W1703346276 endingPage "124" @default.
- W1703346276 startingPage "119" @default.
- W1703346276 abstract "The cytological diagnosis of follicular neoplasm is a common finding in fine needle aspiration cytology (FNAC) of thyroid nodules and includes benign disease as well as differentiated thyroid cancer. The aim of the study is to determine if thyrotropin is a predictive factor for a malignant nature of follicular neoplasm. Patients, methods: The records of 119 patients with follicular neoplasm on FNAC, who underwent surgery for final diagnosis, were reviewed retrospectively. The predictive value of serum parameters including thyrotropin, thyroglobulin, and anti-thyroid antibodies, ultrasonographic criteria and clinical variables was evaluated by univariate analysis and logistic regression analysis. Results, discussion: Patients with malignant nodules showed a higher thyrotropin concentration compared to patients with benign nodules (median 1.6 mU/l, interquartile range 1.4–3.0 mU/l vs. median 1.2 mU/l, interquartile range 0.8–1.6 mU/l, p < 0.01). ROC-analysis of thyrotropin revealed an optimal cut off value to differentiate benign and malignant nodules of 1.34 mU/l. The incidence of malignancy was 30.3% for a thyrotropin concentration higher than 1.34 mU/l compared to 6.4% for a thyrotropin concentration lower than or equal to 1.34 mU/l. On univariate analysis thyroglobulin higher than 300 ng/ml, positive anti-thyroid antibodies, hypoechogenicity, and ill-defined margins, respectively, were also significantly associated with malignancy. On logistic regression analysis higher thyrotropin concentrations, ill-defined margins, and thyroglobulin higher than 300 ng/ml, respectively, were independent predictive factors for malignancy (OR 20.0, 10.7, and 22.7, respectively). Conclusion: Higher thyrotropin concentrations are predictive for a malignant nature of follicular neoplasm." @default.
- W1703346276 created "2016-06-24" @default.
- W1703346276 creator A5008791494 @default.
- W1703346276 creator A5009302505 @default.
- W1703346276 creator A5038480248 @default.
- W1703346276 creator A5054232549 @default.
- W1703346276 creator A5070634770 @default.
- W1703346276 creator A5074316327 @default.
- W1703346276 date "2012-01-01" @default.
- W1703346276 modified "2023-09-26" @default.
- W1703346276 title "Risk of malignancy in follicular thyroid neoplasm: predictive value of thyrotropin." @default.
- W1703346276 cites W182610907 @default.
- W1703346276 cites W1965300587 @default.
- W1703346276 cites W1968542306 @default.
- W1703346276 cites W1972559391 @default.
- W1703346276 cites W1977049981 @default.
- W1703346276 cites W1982564796 @default.
- W1703346276 cites W1984885522 @default.
- W1703346276 cites W1988929259 @default.
- W1703346276 cites W1993902933 @default.
- W1703346276 cites W2007784868 @default.
- W1703346276 cites W2008597453 @default.
- W1703346276 cites W2013821863 @default.
- W1703346276 cites W2017000262 @default.
- W1703346276 cites W2017615299 @default.
- W1703346276 cites W2029719955 @default.
- W1703346276 cites W2031278384 @default.
- W1703346276 cites W2033650650 @default.
- W1703346276 cites W2035919693 @default.
- W1703346276 cites W2042330026 @default.
- W1703346276 cites W2042700043 @default.
- W1703346276 cites W2047633609 @default.
- W1703346276 cites W2053763440 @default.
- W1703346276 cites W2055714790 @default.
- W1703346276 cites W2058111608 @default.
- W1703346276 cites W2071924199 @default.
- W1703346276 cites W2085007333 @default.
- W1703346276 cites W2094840415 @default.
- W1703346276 cites W2096469512 @default.
- W1703346276 cites W2105705771 @default.
- W1703346276 cites W2108884031 @default.
- W1703346276 cites W2132135787 @default.
- W1703346276 cites W2132999954 @default.
- W1703346276 cites W2136165545 @default.
- W1703346276 cites W2139752359 @default.
- W1703346276 cites W2152461684 @default.
- W1703346276 cites W2154186014 @default.
- W1703346276 cites W2209189614 @default.
- W1703346276 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22526481" @default.
- W1703346276 hasPublicationYear "2012" @default.
- W1703346276 type Work @default.
- W1703346276 sameAs 1703346276 @default.
- W1703346276 citedByCount "2" @default.
- W1703346276 countsByYear W17033462762016 @default.
- W1703346276 countsByYear W17033462762017 @default.
- W1703346276 crossrefType "journal-article" @default.
- W1703346276 hasAuthorship W1703346276A5008791494 @default.
- W1703346276 hasAuthorship W1703346276A5009302505 @default.
- W1703346276 hasAuthorship W1703346276A5038480248 @default.
- W1703346276 hasAuthorship W1703346276A5054232549 @default.
- W1703346276 hasAuthorship W1703346276A5070634770 @default.
- W1703346276 hasAuthorship W1703346276A5074316327 @default.
- W1703346276 hasConcept C119060515 @default.
- W1703346276 hasConcept C126322002 @default.
- W1703346276 hasConcept C126838900 @default.
- W1703346276 hasConcept C142724271 @default.
- W1703346276 hasConcept C144301174 @default.
- W1703346276 hasConcept C151956035 @default.
- W1703346276 hasConcept C2778835679 @default.
- W1703346276 hasConcept C2779022025 @default.
- W1703346276 hasConcept C2779399171 @default.
- W1703346276 hasConcept C2779761222 @default.
- W1703346276 hasConcept C38180746 @default.
- W1703346276 hasConcept C526584372 @default.
- W1703346276 hasConcept C71924100 @default.
- W1703346276 hasConcept C90924648 @default.
- W1703346276 hasConceptScore W1703346276C119060515 @default.
- W1703346276 hasConceptScore W1703346276C126322002 @default.
- W1703346276 hasConceptScore W1703346276C126838900 @default.
- W1703346276 hasConceptScore W1703346276C142724271 @default.
- W1703346276 hasConceptScore W1703346276C144301174 @default.
- W1703346276 hasConceptScore W1703346276C151956035 @default.
- W1703346276 hasConceptScore W1703346276C2778835679 @default.
- W1703346276 hasConceptScore W1703346276C2779022025 @default.
- W1703346276 hasConceptScore W1703346276C2779399171 @default.
- W1703346276 hasConceptScore W1703346276C2779761222 @default.
- W1703346276 hasConceptScore W1703346276C38180746 @default.
- W1703346276 hasConceptScore W1703346276C526584372 @default.
- W1703346276 hasConceptScore W1703346276C71924100 @default.
- W1703346276 hasConceptScore W1703346276C90924648 @default.
- W1703346276 hasIssue "4" @default.
- W1703346276 hasLocation W17033462761 @default.
- W1703346276 hasOpenAccess W1703346276 @default.
- W1703346276 hasPrimaryLocation W17033462761 @default.
- W1703346276 hasRelatedWork W1969765890 @default.
- W1703346276 hasRelatedWork W1970608240 @default.
- W1703346276 hasRelatedWork W1978216844 @default.
- W1703346276 hasRelatedWork W1979420670 @default.