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- W170442564 abstract "The antidiabetic activity of Glibenclamide loaded liposomes was investigated in model of alloxan-induced diabetes inrats. The blood glucose level was measured at 0 h and 1, 2, 4, 6, 8, 10, 12, 14 and 16h after the treatment. The alloxan??? diabetic rats showed signifi cant reduction in blood glucose level, after treatment with Glibenclamide loaded liposomesand orally Glibenclamide (used as standard) as compared to diabetic control. The antidiabetic effect of liposomes wascompared with the reference standard drug Glibenclamide (5mg/kg). In conclusion, our result showed that the liposomesloaded glibenclamide when administered by i.p. may reduce blood glucose level. These results suggested the validity ofclinical use of Glibenclamide loaded liposomes." @default.
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- W170442564 date "2007-04-20" @default.
- W170442564 modified "2023-09-27" @default.
- W170442564 title "Efectos antidiabéticos de liposomas cargados con glibenclamida en ratas con diabetes inducida por alloxan" @default.
- W170442564 cites W2038087749 @default.
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- W170442564 doi "https://doi.org/10.30827/ars.v48i1.4976" @default.
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