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- W1708515172 abstract "Introduction Type 2 diabetes is a prevalent and important cardiovascular risk factor [1], and it is well known that patients with established diabetes run a cardiovascular risk between two and four times greater than that run by non-diabetics. It is therefore of importance to prevent the development of type 2 diabetes if possible by an appropriate lifestyle and by a careful selection of antihypertensive drugs in patients at risk, such as those with the metabolic syndrome and hypertension. Observational studies have shown that the risk of drug-induced hyperglycaemia is in fact equal to already existing hyperglycaemia and overt type 2 diabetes during follow-up [2]. Data from the Framingham cohort have also shown that approximately 15–18% of hypertensive patients were “glucose intolerant” and that this may contribute to the increased cardiovascular risk in hypertensive patients [3]. It is therefore of interest to investigate the issue of whether different antihypertensive treatment regimens have different effects on glucose metabolism and the development of diabetes mellitus." @default.
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- W1708515172 date "2006-01-01" @default.
- W1708515172 modified "2023-10-02" @default.
- W1708515172 title "Prevention of type 2 diabetes mellitus with antihypertensive drugs." @default.
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