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• W1710343995 endingPage "386" @default.
• W1710343995 startingPage "375" @default.
• W1710343995 abstract "The nucleotide sequence of the Saccharomyces cerevisiae ARO1 gene which encodes the arom multifunctional enzyme has been determined. The protein sequence deduced for the pentafunctional arom polypeptide is 1588 amino acids in length and has a calculated Mr of 174555. Functional regions within the polypeptide chain have been identified by comparison with the sequences of the five monofunctional Escherichia coli enzymes whose activities correspond with those of the arom multifunctional enzyme. The observed homologies demonstrate that the arom polypeptide is a mosaic of functional domains and are consistent with the hypothesis that the ARO1 gene evolved by the linking of ancestral E. coli-like genes." @default.
• W1710343995 created "2016-06-24" @default.
• W1710343995 creator A5015311778 @default.
• W1710343995 creator A5050728163 @default.
• W1710343995 creator A5069445271 @default.
• W1710343995 date "1987-09-01" @default.
• W1710343995 modified "2023-10-18" @default.
• W1710343995 title "The pentafunctional <i>arom</i> enzyme of <i>Saccharomyces cerevisiae</i> is a mosaic of monofunctional domains" @default.
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• W1710343995 doi "https://doi.org/10.1042/bj2460375" @default.
• W1710343995 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1148286" @default.
• W1710343995 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2825635" @default.
• W1710343995 hasPublicationYear "1987" @default.
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