FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1710553562> ?p ?o ?g. }

• W1710553562 endingPage "504" @default.
• W1710553562 startingPage "499" @default.
• W1710553562 abstract "Butyrate, a product of colonic bacterial flora, functions as an antiproliferative agent and induces cell differentiation in a variety of cell types. In the present study, the effects of butyrate on cell growth and expression of alpha-fetoprotein (AFP) and albumin genes in HuH-7 human hepatoma cells were investigated.The HuH-7 cells were treated with sodium butyrate (0-1 mmol/L), and numbers of viable cells were counted at 24, 48, and 72 hours after treatment. To elucidate the effects of sodium butyrate on AFP and albumin gene expression, Northern blotting and transient chloramphenicol acetyltransferase plasmid transfection experiments were performed.Cell growth was dose dependently inhibited by sodium butyrate. By Northern blot analysis, the level of AFP messenger RNA was reduced by treatment with sodium butyrate, whereas the level of albumin messenger RNA was elevated by this treatment. In transient chloramphenicol acetyltransferase plasmid transfection experiments, sodium butyrate repressed the AFP promoter activity but did not change the AFP enhancer or silencer activities. In contrast, the albumin promoter activity was stimulated by sodium butyrate.These results suggest that butyrate leads to the reciprocal differentiating regulation of AFP and albumin gene expression at the transcriptional level in human hepatoma cells." @default.
• W1710553562 created "2016-06-24" @default.
• W1710553562 creator A5028525487 @default.
• W1710553562 creator A5033980070 @default.
• W1710553562 creator A5051094265 @default.
• W1710553562 creator A5061244847 @default.
• W1710553562 creator A5061344672 @default.
• W1710553562 creator A5066183432 @default.
• W1710553562 creator A5069787818 @default.
• W1710553562 creator A5071604510 @default.
• W1710553562 creator A5084850583 @default.
• W1710553562 date "1994-08-01" @default.
• W1710553562 modified "2023-09-24" @default.
• W1710553562 title "Reciprocal regulation of α-fetoprotein and albumin gene expression by butyrate in human hepatoma cells" @default.
• W1710553562 cites W1507205054 @default.
• W1710553562 cites W1532278930 @default.
• W1710553562 cites W1567981986 @default.
• W1710553562 cites W1586750917 @default.
• W1710553562 cites W1587775583 @default.
• W1710553562 cites W1594157248 @default.
• W1710553562 cites W1640373721 @default.
• W1710553562 cites W1841064011 @default.
• W1710553562 cites W1970126718 @default.
• W1710553562 cites W1978573961 @default.
• W1710553562 cites W1981854303 @default.
• W1710553562 cites W1989727210 @default.
• W1710553562 cites W1989907307 @default.
• W1710553562 cites W1990022157 @default.
• W1710553562 cites W1993706334 @default.
• W1710553562 cites W1997025763 @default.
• W1710553562 cites W1998220537 @default.
• W1710553562 cites W2011130417 @default.
• W1710553562 cites W2019104206 @default.
• W1710553562 cites W2041797124 @default.
• W1710553562 cites W2077107574 @default.
• W1710553562 cites W2093410497 @default.
• W1710553562 cites W2093634017 @default.
• W1710553562 cites W2100805638 @default.
• W1710553562 cites W2107270084 @default.
• W1710553562 cites W2114783885 @default.
• W1710553562 cites W2119419566 @default.
• W1710553562 cites W2135232490 @default.
• W1710553562 cites W2144206181 @default.
• W1710553562 cites W2151087783 @default.
• W1710553562 cites W2238140388 @default.
• W1710553562 cites W2313408830 @default.
• W1710553562 cites W2313825712 @default.
• W1710553562 cites W4230714071 @default.
• W1710553562 cites W4245881395 @default.
• W1710553562 doi "https://doi.org/10.1016/0016-5085(94)90177-5" @default.
• W1710553562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7518784" @default.
• W1710553562 hasPublicationYear "1994" @default.
• W1710553562 type Work @default.
• W1710553562 sameAs 1710553562 @default.
• W1710553562 citedByCount "43" @default.
• W1710553562 countsByYear W17105535622012 @default.
• W1710553562 countsByYear W17105535622013 @default.
• W1710553562 countsByYear W17105535622015 @default.
• W1710553562 countsByYear W17105535622016 @default.
• W1710553562 countsByYear W17105535622017 @default.
• W1710553562 countsByYear W17105535622018 @default.
• W1710553562 countsByYear W17105535622020 @default.
• W1710553562 crossrefType "journal-article" @default.
• W1710553562 hasAuthorship W1710553562A5028525487 @default.
• W1710553562 hasAuthorship W1710553562A5033980070 @default.
• W1710553562 hasAuthorship W1710553562A5051094265 @default.
• W1710553562 hasAuthorship W1710553562A5061244847 @default.
• W1710553562 hasAuthorship W1710553562A5061344672 @default.
• W1710553562 hasAuthorship W1710553562A5066183432 @default.
• W1710553562 hasAuthorship W1710553562A5069787818 @default.
• W1710553562 hasAuthorship W1710553562A5071604510 @default.
• W1710553562 hasAuthorship W1710553562A5084850583 @default.
• W1710553562 hasConcept C100544194 @default.
• W1710553562 hasConcept C104317684 @default.
• W1710553562 hasConcept C105580179 @default.
• W1710553562 hasConcept C1491633281 @default.
• W1710553562 hasConcept C150194340 @default.
• W1710553562 hasConcept C153911025 @default.
• W1710553562 hasConcept C161733203 @default.
• W1710553562 hasConcept C177707886 @default.
• W1710553562 hasConcept C185592680 @default.
• W1710553562 hasConcept C2776979534 @default.
• W1710553562 hasConcept C2778942008 @default.
• W1710553562 hasConcept C2780730277 @default.
• W1710553562 hasConcept C54009773 @default.
• W1710553562 hasConcept C55493867 @default.
• W1710553562 hasConcept C86803240 @default.
• W1710553562 hasConceptScore W1710553562C100544194 @default.
• W1710553562 hasConceptScore W1710553562C104317684 @default.
• W1710553562 hasConceptScore W1710553562C105580179 @default.
• W1710553562 hasConceptScore W1710553562C1491633281 @default.
• W1710553562 hasConceptScore W1710553562C150194340 @default.
• W1710553562 hasConceptScore W1710553562C153911025 @default.
• W1710553562 hasConceptScore W1710553562C161733203 @default.
• W1710553562 hasConceptScore W1710553562C177707886 @default.
• W1710553562 hasConceptScore W1710553562C185592680 @default.
• W1710553562 hasConceptScore W1710553562C2776979534 @default.
• W1710553562 hasConceptScore W1710553562C2778942008 @default.

• next