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- W171110972 abstract "Hot-melt extrusion is a proven pharmaceutical processing technology, enabling the formation of matrices and structures designed to control drug release. Controlled drug release formulations are important for reducing side effects, improving bioavailability, and patient compliance. Melt extrusion has been applied in the production of various controlled-release dosage forms: including pellets, tablets, films, and drug reservoirs. Controlled-release dosage forms prepared by extrusion have been demonstrated for oral delivery as well as in producing implants and transmucosal devices. This chapter reviews extruded controlled-release dosage forms, highlighting the importance of material properties and structure. The mechanisms by which drugs are released from different materials and structures are reviewed using examples from current literature." @default.
- W171110972 created "2016-06-24" @default.
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- W171110972 date "2013-01-01" @default.
- W171110972 modified "2023-09-23" @default.
- W171110972 title "Melt Extruded Controlled Release Dosage Forms" @default.
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- W171110972 doi "https://doi.org/10.1007/978-1-4614-8432-5_10" @default.
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