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- W171230761 abstract "Context-dependent nature of biological phenomena are well documented in every branch of biology. While there have been few previous attempts to (implicitly) model various facets of biological context-dependence, a formal and general mathematical construct to model the wide spectrum of context-dependence, eludes the students of biology. An objective and rigorous model, from both 'bottom-up' as well as 'top-down' perspective, is proposed here to serve as the template to describe the various kinds of context-dependence that we encounter in different branches of biology. Interactions between biological contexts was found to be transitive but non-commutative. It is found that a hierarchical nature of dependence amongst the biological contexts models the emergent biological properties efficiently. Reasons for these findings are provided with a general model to describe biological reality. Scheme to algorithmically implement the hierarchic structure of organization of biological contexts was achieved with a construct named 'Context tree'. A 'Context tree' based analysis of context interactions among biophysical factors influencing protein structure was performed." @default.
- W171230761 created "2016-06-24" @default.
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- W171230761 date "2009-02-04" @default.
- W171230761 modified "2023-09-24" @default.
- W171230761 title "A mathematical model to describe context-dependence in Biology" @default.
- W171230761 hasPublicationYear "2009" @default.
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