FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W17123896> ?p ?o ?g. }

• W17123896 endingPage "1873" @default.
• W17123896 startingPage "1867" @default.
• W17123896 abstract "This study investigated the occurrence of intraluminal thrombus and its potential implications with facilitated percutaneous coronary interventions (fPCIs). The effect of fPCI on the presence and consequences of intraluminal thrombus is unknown. Thrombolysis In Myocardial Infarction (TIMI) flow grade, frame count, and thrombus grade; distal embolization; and slow flow in the infarct-related artery were assessed in a blinded fashion on coronary angiograms in 1,342 patients from the ASSENT-4 PCI (Assessment of the Safety and Efficacy of a New Treatment Strategy With Percutaneous Coronary Intervention) trial. Residual TIMI thrombus grade ≥2 and/or distal embolization and/or slow flow, reflecting thrombus burden (TB), following PCI were correlated with ST-segment resolution, epicardial blood flow, and clinical outcome. The clinical composite endpoint was death, congestive heart failure, or shock. In the fPCI group, more TIMI flow grade 2/3 in the infarct-related artery at the first angiogram (73.7% vs. 33.4%, p < 0.001) and a higher TB following PCI (19.7% vs. 13.4%, p = 0.002) were found in comparison with the primary PCI group. Post-PCI TIMI thrombus grade was significantly associated with ST-segment resolution (p < 0.001) and TIMI frame count (p < 0.0001) in both groups. In the fPCI group, the presence of post-PCI thrombus was associated with a significantly worse outcome at 90 days (clinical composite endpoint: 32.1% vs. 18.6%, p = 0.023). Multivariable logistic regression showed that facilitation with tenecteplase (p = 0.005) and TB (odds ratio: 2.43, 95% confidence interval: 1.30 to 4.51, p = 0.0052) were independent predictors of 90-day mortality. In ASSENT-4 PCI, despite more patency, residual TB was significantly higher in fPCI patients and was associated with less efficient tissue reperfusion and worse clinical outcomes. (A Trial Evaluating the Efficacy and Safety of Tenecteplase Together With Unfractionated Heparin Prior to Early Percutaneous Coronary Intervention [PCI] as Compared to Standard Primary PCI in Patients With Acute Myocardial Infarction [ASSENT-4 PCI]; NCT00168792)" @default.
• W17123896 created "2016-06-24" @default.
• W17123896 creator A5000622416 @default.
• W17123896 creator A5013303634 @default.
• W17123896 creator A5028904200 @default.
• W17123896 creator A5037527199 @default.
• W17123896 creator A5038384001 @default.
• W17123896 creator A5039649958 @default.
• W17123896 creator A5078207171 @default.
• W17123896 creator A5087317612 @default.
• W17123896 creator A5090147492 @default.
• W17123896 date "2011-05-01" @default.
• W17123896 modified "2023-09-25" @default.
• W17123896 title "Intraluminal Thrombus in Facilitated Versus Primary Percutaneous Coronary Intervention" @default.
• W17123896 cites W1519563600 @default.
• W17123896 cites W1973760359 @default.
• W17123896 cites W1986689269 @default.
• W17123896 cites W2020527746 @default.
• W17123896 cites W2037709494 @default.
• W17123896 cites W2059289792 @default.
• W17123896 cites W2062885533 @default.
• W17123896 cites W2067329489 @default.
• W17123896 cites W2096711488 @default.
• W17123896 cites W2126341802 @default.
• W17123896 cites W2150595619 @default.
• W17123896 cites W2164085712 @default.
• W17123896 cites W2469689849 @default.
• W17123896 cites W2523584376 @default.
• W17123896 cites W2573347960 @default.
• W17123896 doi "https://doi.org/10.1016/j.jacc.2010.10.061" @default.
• W17123896 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21545942" @default.
• W17123896 hasPublicationYear "2011" @default.
• W17123896 type Work @default.
• W17123896 sameAs 17123896 @default.
• W17123896 citedByCount "31" @default.
• W17123896 countsByYear W171238962012 @default.
• W17123896 countsByYear W171238962013 @default.
• W17123896 countsByYear W171238962014 @default.
• W17123896 countsByYear W171238962015 @default.
• W17123896 countsByYear W171238962016 @default.
• W17123896 countsByYear W171238962017 @default.
• W17123896 countsByYear W171238962018 @default.
• W17123896 countsByYear W171238962019 @default.
• W17123896 countsByYear W171238962020 @default.
• W17123896 countsByYear W171238962021 @default.
• W17123896 countsByYear W171238962022 @default.
• W17123896 crossrefType "journal-article" @default.
• W17123896 hasAuthorship W17123896A5000622416 @default.
• W17123896 hasAuthorship W17123896A5013303634 @default.
• W17123896 hasAuthorship W17123896A5028904200 @default.
• W17123896 hasAuthorship W17123896A5037527199 @default.
• W17123896 hasAuthorship W17123896A5038384001 @default.
• W17123896 hasAuthorship W17123896A5039649958 @default.
• W17123896 hasAuthorship W17123896A5078207171 @default.
• W17123896 hasAuthorship W17123896A5087317612 @default.
• W17123896 hasAuthorship W17123896A5090147492 @default.
• W17123896 hasBestOaLocation W171238961 @default.
• W17123896 hasConcept C126322002 @default.
• W17123896 hasConcept C164705383 @default.
• W17123896 hasConcept C203092338 @default.
• W17123896 hasConcept C2777995511 @default.
• W17123896 hasConcept C2779581417 @default.
• W17123896 hasConcept C2780400711 @default.
• W17123896 hasConcept C2781362458 @default.
• W17123896 hasConcept C45393284 @default.
• W17123896 hasConcept C500558357 @default.
• W17123896 hasConcept C535046627 @default.
• W17123896 hasConcept C71924100 @default.
• W17123896 hasConceptScore W17123896C126322002 @default.
• W17123896 hasConceptScore W17123896C164705383 @default.
• W17123896 hasConceptScore W17123896C203092338 @default.
• W17123896 hasConceptScore W17123896C2777995511 @default.
• W17123896 hasConceptScore W17123896C2779581417 @default.
• W17123896 hasConceptScore W17123896C2780400711 @default.
• W17123896 hasConceptScore W17123896C2781362458 @default.
• W17123896 hasConceptScore W17123896C45393284 @default.
• W17123896 hasConceptScore W17123896C500558357 @default.
• W17123896 hasConceptScore W17123896C535046627 @default.
• W17123896 hasConceptScore W17123896C71924100 @default.
• W17123896 hasFunder F4320315666 @default.
• W17123896 hasIssue "19" @default.
• W17123896 hasLocation W171238961 @default.
• W17123896 hasLocation W171238962 @default.
• W17123896 hasOpenAccess W17123896 @default.
• W17123896 hasPrimaryLocation W171238961 @default.
• W17123896 hasRelatedWork W2094308415 @default.
• W17123896 hasRelatedWork W2127687375 @default.
• W17123896 hasRelatedWork W2333158738 @default.
• W17123896 hasRelatedWork W2363980427 @default.
• W17123896 hasRelatedWork W2366428215 @default.
• W17123896 hasRelatedWork W2384974294 @default.
• W17123896 hasRelatedWork W2390071281 @default.
• W17123896 hasRelatedWork W2394748619 @default.
• W17123896 hasRelatedWork W4385416086 @default.
• W17123896 hasRelatedWork W2413908167 @default.
• W17123896 hasVolume "57" @default.
• W17123896 isParatext "false" @default.
• W17123896 isRetracted "false" @default.

• next