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- W1712876258 endingPage "96" @default.
- W1712876258 startingPage "372" @default.
- W1712876258 abstract "Individuals use and misuse alcohol (and other drugs) because of the pharmacologically mediated effects these substances have on the operation of 4 psychobiological systems, mediating response to motivationally relevant unconditioned and conditioned stimuli. These 4 systems have unique neuroanatomical structure, biochemical modes of operation, association with affect, behavior and cognition, and responsiveness to drugs of abuse. Individual variation in the operation of these systems determines individual susceptibility to initiation and maintenance of drug use and abuse. Sources of such variation differ, in a vitally important fashion, in various specific populations of individuals at heightened risk for drug abuse. Nonalcoholic sons of male alcoholics, with multigenerational family histories of male alcoholism, appear to be at heightened risk for the development of alcohol abuse because alcohol eliminates their heightened response to threat, and because they are hypersensitive to ethanol's psychomotor stimulant effects. Anxiety-sensitive individuals also appear attracted to alcohol for its anxiolytic properties. Many other important sources of idiosyncratic variability exist. Detailed analysis of such sources may lead to the development of more effective prevention and treatment programs." @default.
- W1712876258 created "2016-06-24" @default.
- W1712876258 creator A5083234375 @default.
- W1712876258 creator A5089696506 @default.
- W1712876258 date "1995-11-01" @default.
- W1712876258 modified "2023-09-29" @default.
- W1712876258 title "Alcoholism: the role of different motivational systems." @default.
- W1712876258 cites W1500883398 @default.
- W1712876258 cites W1522318572 @default.
- W1712876258 cites W1532346573 @default.
- W1712876258 cites W156199230 @default.
- W1712876258 cites W160982706 @default.
- W1712876258 cites W1709742262 @default.
- W1712876258 cites W177581319 @default.
- W1712876258 cites W1808308480 @default.
- W1712876258 cites W1836384072 @default.
- W1712876258 cites W1927204052 @default.
- W1712876258 cites W1964357729 @default.
- W1712876258 cites W1964914962 @default.
- W1712876258 cites W1969763801 @default.
- W1712876258 cites W1970344711 @default.
- W1712876258 cites W1970541082 @default.
- W1712876258 cites W1971464615 @default.
- W1712876258 cites W1972726498 @default.
- W1712876258 cites W1975308148 @default.
- W1712876258 cites W1976165599 @default.
- W1712876258 cites W1977188405 @default.
- W1712876258 cites W1977436056 @default.
- W1712876258 cites W1982564808 @default.
- W1712876258 cites W1982995874 @default.
- W1712876258 cites W1983513632 @default.
- W1712876258 cites W1983955342 @default.
- W1712876258 cites W1985349171 @default.
- W1712876258 cites W1985708559 @default.
- W1712876258 cites W1987562848 @default.
- W1712876258 cites W1990530036 @default.
- W1712876258 cites W1994059964 @default.
- W1712876258 cites W1995237618 @default.
- W1712876258 cites W1995368779 @default.
- W1712876258 cites W1996970619 @default.
- W1712876258 cites W2001966367 @default.
- W1712876258 cites W2002015575 @default.
- W1712876258 cites W2004422480 @default.
- W1712876258 cites W2004687357 @default.
- W1712876258 cites W2004984114 @default.
- W1712876258 cites W2005956227 @default.
- W1712876258 cites W2007126717 @default.
- W1712876258 cites W2008439054 @default.
- W1712876258 cites W2009829899 @default.
- W1712876258 cites W2009856101 @default.
- W1712876258 cites W2010113700 @default.
- W1712876258 cites W2014445850 @default.
- W1712876258 cites W2018544235 @default.
- W1712876258 cites W2019336568 @default.
- W1712876258 cites W2022109686 @default.
- W1712876258 cites W2024062859 @default.
- W1712876258 cites W2025331966 @default.
- W1712876258 cites W2027256318 @default.
- W1712876258 cites W2028226906 @default.
- W1712876258 cites W2028747026 @default.
- W1712876258 cites W2030039904 @default.
- W1712876258 cites W2035369365 @default.
- W1712876258 cites W2038805250 @default.
- W1712876258 cites W2039215581 @default.
- W1712876258 cites W2039237410 @default.
- W1712876258 cites W2039544897 @default.
- W1712876258 cites W2040904085 @default.
- W1712876258 cites W2041082741 @default.
- W1712876258 cites W2041086676 @default.
- W1712876258 cites W2041197436 @default.
- W1712876258 cites W2041247164 @default.
- W1712876258 cites W2042144777 @default.
- W1712876258 cites W2047108558 @default.
- W1712876258 cites W2048280165 @default.
- W1712876258 cites W2055691150 @default.
- W1712876258 cites W2056971179 @default.
- W1712876258 cites W2061161259 @default.
- W1712876258 cites W2061344417 @default.
- W1712876258 cites W2061506859 @default.
- W1712876258 cites W2061707789 @default.
- W1712876258 cites W2063003108 @default.
- W1712876258 cites W2064132586 @default.
- W1712876258 cites W2068007070 @default.
- W1712876258 cites W2068147284 @default.
- W1712876258 cites W2071805163 @default.
- W1712876258 cites W2072176522 @default.
- W1712876258 cites W2072508645 @default.
- W1712876258 cites W2073537077 @default.
- W1712876258 cites W2076258469 @default.
- W1712876258 cites W2076981513 @default.
- W1712876258 cites W2079727820 @default.
- W1712876258 cites W2084785057 @default.
- W1712876258 cites W2084917270 @default.
- W1712876258 cites W2088829922 @default.
- W1712876258 cites W2091169166 @default.
- W1712876258 cites W2091383986 @default.
- W1712876258 cites W2092051580 @default.
- W1712876258 cites W2093404642 @default.