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- W1713011645 abstract "Centenarians, though rare at a prevalence of approximately one per 10,000 in industrialized countries, are among the fastest growing segment of our population. Familial studies indicate that exceptional longevity runs strongly in families, but as of yet, few genetic variations have been found to account for this survival advantage. It is likely that the prevalence of centenarians is increasing because achieving exceptional old age is multifactorial. A number of factors important to such longevity are becoming more prevalent with modern public health measures and interventions. Such a multiple trait model would predict that the more extreme the phenotype, the more likely discernible environmental and genetic characteristics are to be discovered that are important to achieving very old age, much of it disability-free. Thus studies of families highly clustered for longevity or studies of supercentenarains, people age 110 and older, hold promise of facilitating such discoveries." @default.
- W1713011645 created "2016-06-24" @default.
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- W1713011645 date "2006-01-01" @default.
- W1713011645 modified "2023-09-24" @default.
- W1713011645 title "Human Models of Longevity" @default.
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- W1713011645 doi "https://doi.org/10.1016/b978-012369391-4/50048-5" @default.
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