FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1713048017> ?p ?o ?g. }

• W1713048017 endingPage "420" @default.
• W1713048017 startingPage "408" @default.
• W1713048017 abstract "Detailed restriction endonuclease maps were developed for Harvey murine sarcoma virus (Ha-MuSV) DNA (clone H-1), molecularly closed at its unique EcoRI site in pBR322, for three nonoverlapping subgenomic HindIII clones which together span the entire H-1 clone and for a molecularly cloned DNA copy of a portion of rat 30S RNA (which represents the majority of the rat genetic sequences in Ha-MuSV). Molecular hybridization of the 30S clone to small restriction fragments of clone H-1 revealed a 0.9-to-1.0-kilobase pair region in the 5' half of the Ha-MuSV genome not homologous to the 30S clone, although the 30S clone did contain related sequences in Ha-MuSV on both sides of this nonhomologous region. By using cloned sequences from a segment of the Ha-MuSV nonhomology region as a probe for hybridization to Southern blots of DNA from rat, mouse, bat, and chicken cells, one to three bands were detected in DNA of each species. By contrast, the 30S clone DNA was highly related to many sequences in rat DNA, partially related to fewer mouse DNA sequences, and homologous only to one to three bands in bat and chicken DNA. Earlier work had shown that the 5' half of the Ha-MuSV genome coded for transformation and for the viral p21 protein (Chang et al., J. Virol. 35: 76--92, 1980; Wei et al., Proc. Natl. Acad. Sci. U.S.A., in press). We used two subgenomic HindIII clones whose shared HindIII site mapped within the 5' region of clone H-1 nonhomologous to the 30S clone to test whether the nonhomologous segment might encode the transforming and p21 functions. Although neither of the subgenomic HindIII fragments by themselves induced transformation, ligation of these two nontransforming DNAs to each other did restore p21-mediated transformation. A conclusion consistent with these results is that a region in the 5' half of the Ha-MuSV genome evolutionarily distinct from and not present in rat 30S RNA is essential for transformation and for p21 encoding." @default.
• W1713048017 created "2016-06-24" @default.
• W1713048017 creator A5009471069 @default.
• W1713048017 creator A5029227372 @default.
• W1713048017 creator A5039264253 @default.
• W1713048017 creator A5040906660 @default.
• W1713048017 creator A5053626123 @default.
• W1713048017 creator A5074566412 @default.
• W1713048017 creator A5086620768 @default.
• W1713048017 creator A5090914300 @default.
• W1713048017 date "1980-11-01" @default.
• W1713048017 modified "2023-10-14" @default.
• W1713048017 title "Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus" @default.
• W1713048017 cites W1484483886 @default.
• W1713048017 cites W1533105748 @default.
• W1713048017 cites W1555244538 @default.
• W1713048017 cites W1587981028 @default.
• W1713048017 cites W1592665250 @default.
• W1713048017 cites W1594780052 @default.
• W1713048017 cites W1603649794 @default.
• W1713048017 cites W1631202616 @default.
• W1713048017 cites W1689612166 @default.
• W1713048017 cites W1694758169 @default.
• W1713048017 cites W1754450379 @default.
• W1713048017 cites W1784188086 @default.
• W1713048017 cites W1800921654 @default.
• W1713048017 cites W1875529355 @default.
• W1713048017 cites W1912820173 @default.
• W1713048017 cites W1965372133 @default.
• W1713048017 cites W1967446284 @default.
• W1713048017 cites W1978812213 @default.
• W1713048017 cites W1980613817 @default.
• W1713048017 cites W1987656535 @default.
• W1713048017 cites W1998132110 @default.
• W1713048017 cites W2003591463 @default.
• W1713048017 cites W2008095094 @default.
• W1713048017 cites W2014356084 @default.
• W1713048017 cites W2022623820 @default.
• W1713048017 cites W2031946492 @default.
• W1713048017 cites W2033958335 @default.
• W1713048017 cites W2035520923 @default.
• W1713048017 cites W2043860143 @default.
• W1713048017 cites W2061906765 @default.
• W1713048017 cites W2063450941 @default.
• W1713048017 cites W2069717128 @default.
• W1713048017 cites W2083715166 @default.
• W1713048017 cites W2094082118 @default.
• W1713048017 cites W2107536554 @default.
• W1713048017 cites W2111729024 @default.
• W1713048017 cites W2112269133 @default.
• W1713048017 cites W2117886028 @default.
• W1713048017 cites W2142617031 @default.
• W1713048017 doi "https://doi.org/10.1128/jvi.36.2.408-420.1980" @default.
• W1713048017 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/353657" @default.
• W1713048017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6253666" @default.
• W1713048017 hasPublicationYear "1980" @default.
• W1713048017 type Work @default.
• W1713048017 sameAs 1713048017 @default.
• W1713048017 citedByCount "372" @default.
• W1713048017 countsByYear W17130480172016 @default.
• W1713048017 countsByYear W17130480172018 @default.
• W1713048017 crossrefType "journal-article" @default.
• W1713048017 hasAuthorship W1713048017A5009471069 @default.
• W1713048017 hasAuthorship W1713048017A5029227372 @default.
• W1713048017 hasAuthorship W1713048017A5039264253 @default.
• W1713048017 hasAuthorship W1713048017A5040906660 @default.
• W1713048017 hasAuthorship W1713048017A5053626123 @default.
• W1713048017 hasAuthorship W1713048017A5074566412 @default.
• W1713048017 hasAuthorship W1713048017A5086620768 @default.
• W1713048017 hasAuthorship W1713048017A5090914300 @default.
• W1713048017 hasBestOaLocation W17130480171 @default.
• W1713048017 hasConcept C104317684 @default.
• W1713048017 hasConcept C128319531 @default.
• W1713048017 hasConcept C130123407 @default.
• W1713048017 hasConcept C141231307 @default.
• W1713048017 hasConcept C151292725 @default.
• W1713048017 hasConcept C153911025 @default.
• W1713048017 hasConcept C159047783 @default.
• W1713048017 hasConcept C189819185 @default.
• W1713048017 hasConcept C54355233 @default.
• W1713048017 hasConcept C552990157 @default.
• W1713048017 hasConcept C81089528 @default.
• W1713048017 hasConcept C86803240 @default.
• W1713048017 hasConceptScore W1713048017C104317684 @default.
• W1713048017 hasConceptScore W1713048017C128319531 @default.
• W1713048017 hasConceptScore W1713048017C130123407 @default.
• W1713048017 hasConceptScore W1713048017C141231307 @default.
• W1713048017 hasConceptScore W1713048017C151292725 @default.
• W1713048017 hasConceptScore W1713048017C153911025 @default.
• W1713048017 hasConceptScore W1713048017C159047783 @default.
• W1713048017 hasConceptScore W1713048017C189819185 @default.
• W1713048017 hasConceptScore W1713048017C54355233 @default.
• W1713048017 hasConceptScore W1713048017C552990157 @default.
• W1713048017 hasConceptScore W1713048017C81089528 @default.
• W1713048017 hasConceptScore W1713048017C86803240 @default.
• W1713048017 hasIssue "2" @default.
• W1713048017 hasLocation W17130480171 @default.
• W1713048017 hasLocation W17130480172 @default.

• next